sporadic alzheimer’s disease (sad) is a multi-factorial disease caused by genetic, epigenetic, environmental and metabolic factors. current understandings of the possible mechanisms of ad such as inflammation and oxidative stresses in the brain have led us to investigation of potential ad therapeutics. currently herbal medicines with fewer side effects comparing to other chemical medicine are i...

introduction: acute renal failure is a common consequence of sepisis due to concurrent renal ischaemia. the role of nitric oxide (no) in endotoxaemia and in ischaemic injury in the kidney is not well defined. material and methods: in this study we have used an animal model of sepsis induced by injection of bacterial lipopolysaccharide (lps) in the rat and measured renal nitric oxide by x-band e...

The level structure of the transitional nucleus $\mathrm{^{217}Ra}$ has been extended with addition around 20 new transitions. discrepancies between placements several transitions reported in earlier studies are resolved. newly-established negative-parity sequence at low excitation energies hints expected parity-doublet structures this nucleus. properties observed simplex bands compared that si...

T-2 toxin, a trichothecene mycotoxin, is considered to be one of the most toxic compounds that are produced by molds, particularly the Fusarium species. Fusarium species have been recognized as a great agricultural problem. They occur worldwide on a variety of plant hosts and cereal grains. The aim of this study was to investigate T-2 toxin-induced liver injury using in situ perfused rat liver....

Cover: The cover image is based on the Research Article Choreito, a Kampo medicine attenuates detrusor overactivity and bladder pain symptoms in rat tranilast-induced interstitial cystitis/bladder syndrome-like model by Yohei Tokita PhD et al., https://doi.org/10.1002/nau.25095.

The objective of this study was to determine the effect Apis dorsata forest honey on liver histopathological changes white rats (Rattus norvegicus) exposed physical stress. This used 24 which were divided into 4 groups. positive control group (C+) only given a stressor and distilled water orally, treatment 1 (T1) + 2g/rat/day, T2 4g/rat/day, T3 6g/rat/day. All treatments carried out within 14 d...

Objective(s): Fluvoxamine is a well-known selective serotonin reuptake inhibitor (SSRI); Despite its anti-inflammatory effect, little is known about the precise mechanisms involved. In our previous work, we found that IP administration of fluvoxamine produced a noticeable anti-inflammatory effect in carrageenan-induced paw edema in rats. In this study, we aimed to evaluate the effect of fluvoxa...

Background: Radiation-induced lung injury is a refractory side effect in lung cancer radiotherapy, the mechanism still remains unclear, hence an appropriate animal mode may become useful to investigate it. Materials and Methods: 50 female Wistar rats were randomly divided into 5 groups, average 10 rats/cage: A. control group B. 3Gy×10f C. 6Gy×5f D. 12.5Gy×1f E.15.3Gy×1f....

In this article, a direct preconditioner is proposed for coupling matrix reconfiguration of bandpass filters with irregular couplings using the coefficient-parameter continuation method. With preconditioner, method can be effectively used filter synthesis and model extraction couplings. dealing practical that contain topology regular cross introduced intentionally or unintentionally, being as s...