effects of inhaled essential oils (eos) cannot be explained by pharmacological mechanisms alone. the study aimed to investigate the effects of pleasantness of and expectancies evoked by eos. a double-blind experiment with a within-subject design was carried out with the participation of 33 volunteering adults (15.2% male; mean age 37.7 ± 10.90 years). participants were exposed to three eos (...

background: hospitalization in the coronary care unit (ccu) is a concern for patients and their companions. different studies have presented conflicting results about the effect of visitors on physiological parameters of patients. the purpose of this study was to determine changes in physiological parameters (systolic and diastolic blood pressure and heart rate) due to presence of visitors at t...

Incidence of coronary artery disease (CAD) increases sharply after menopause in women. Rate pressure product (RPP) is a major determinant of cardiac oxygen consumption. It is an important indicator of ventricular function. RPP varies with exercise. The peak rate pressure product (PRPP) which gives an accurate reflection of the myocardial oxygen demand and myocardial workload is the RPP at peak ...

BACKGROUND Epidemiologic studies suggest a positive association between fine particulate matter and arterial blood pressure, but the results have been inconsistent. OBJECTIVES We investigated the effect of ambient particles on systemic hemodynamics during a 5-hr exposure to concentrated ambient air particles (CAPs) or filtered air (FA) in conscious canines. METHODS Thirteen dogs were repeat...

The manufacture of highly drug-loaded fine globular granules eventually applied for orally disintegrating tablets has been investigated using a unique multi-functional rotor processor with acetaminophen, which was used as a model drug substance. Experimental design and statistical analysis were used to evaluate potential relationships between three key operating parameters (i.e., the binder flo...

An experimental model of postischemic, acute renal failure has been developed in Wistar rats with surface glomeruli, thereby making possible a direct assessment of the mechanisms responsible for the fall in glomerular filtration rate that characterizes this disorder. Whole kidney and cortical single nephron filtration rates were reduced proportionately, on average by approximately 40%, after 3 ...

The aim of the study was to assess the effects of varying the pressurisation rate during noninvasive pressure support ventilation on patients' breathing pattern, inspiratory effort, arterial blood gases, tolerance to ventilation and amount of air leakage. A total of 15 chronic obstructive pulmonary disease patients recovering from an acute episode of hypercapnic acute respiratory failure were s...

High pressure processing is recently applied in the food industry to inactivate spoilage and pathogenic microorganisms. Bacterial cells exhibit various barosensibility, and the role of pressurization, depressurization and constant pressure stage remain unknown. We investigated the effect of high pressure processing on Salmonella typhimurium and Listeria monocytogenes cells at 400 and 500 MPa re...

Recently, a marked increase in the number of acute myocardial infarction cases during winter has been reported. Approximately 53% more cases were reported in winter than during summer [1]. The abrupt rupture of atherosclerotic plaques that occurs during cold exposure has been associated with an increase in sympathetic tone that causes increased blood pressure, heart rate and cardiac workload [2...