BACKGROUND Clinical studies indicate that blood pressure (BP)-lowering effects of radiofrequency (RF) renal denervation (RD) are sustained for up to 2 years, although a recent clinical trial failed to find a major effect compared to sham treatment. In most previous studies, the efficacy of RD has not been assessed. The current study determined whether RD in different regions of the renal artery...

BACKGROUND Although renal denervation (RD) is shown to reduce blood pressure significantly in patients with resistant hypertension, the benefit of RD in prevention of stroke is unknown. We hypothesized that RD can prevent the incidence of stroke and brain injury in hypertensive rats beyond blood pressure lowering. METHODS AND RESULTS High-salt-loaded, stroke-prone, spontaneously hypertensive ...

objective(s):this study aims at exploring cytotoxic activity of different peptides derived from vsvg protein against mcf-7 and mda-mb-231 breast cancer cell lines and human embryonic kidney normal cell (hek 293).    materials and methods: the anticp web server was used to predict anticancer peptides. the cytotoxic activity of peptides with high score (p26, p7) and low score (p19) was examined b...

in determination of particular types of coagulate positive staphylococci (staphylococcus aurous) causing different diseases, especially hospital sepsis and food poisonings; 186 strains of coagulase positive staphylococci from different provinces in iran were phage typed. because of various sources of the strains, the results had some differences, as 15.8 percent or 15 strains separated from chi...

Numerous studies have shown that packet reordering is common, especially in networks with a high degree of parallelism. Reordering of packets decreases the TCP performance of a network, mainly because it leads to overestimation of the congestion of the network. We consider wired networks with transmission that follows predominantly, but not necessarily exclusively, symmetric routing paths, and ...

A3 Note that each of the sets {1}, {2}, . . . , {n} has the desired property. Moreover, for each set S with integer average m that does not contain m, S ∪ {m} also has average m, while for each set T of more than one element with integer average m that contains m, T \{m} also has average m. Thus the subsets other than {1}, {2}, . . . , {n} can be grouped in pairs, so Tn −n is even. A4 (partly d...

Activity of the CFTR channel is regulated by phosphorylation of its regulatory domain (RD). In a previous study, we developed a bicistronic construct called DeltaR-Split CFTR, which encodes the front and back halves of CFTR as separate polypeptides without the RD. These fragments assemble to form a constitutively active CFTR channel. Coexpression of the third fragment corresponding to the missi...

the aim of the study was to determine the resistance patterns of pseudomonas aeruginosa isolates recovered from patients with surgical wounds in hospitals and also to investigate their epidemiological relatedness using molecular typing techniques. twenty pseudomonas sp. isolated from surgical wounds were subjected to antibiotic susceptibility testing by disk diffusion, plasmid profile, sds-page...

pasteurella multocida is known as one of the main organisms causing pneumonia in sheep. as immunity in pasteurellosis is serogroup specific, identification of prevalent capsular group among endemic areas is essential. the aim of this study was to molecular identification and determine of the capsular type of the p. multocida strains isolated from sheep pneumonia in iran. bacteriological and bio...