Coronary disease is the leading killer of individuals worldwide and a leading cause of healthcare expenditure. On a global scale, ischemic heart disease kills over 6 million individuals each year and is projected by the World Health Organization to be the greatest single-disease cause of death worldwide by an increasing margin into 2030. Nearly 17 million Americans (7.6% of the population) have...

D espite aggressive control of modifiable risk factors, recurrent acute coronary syndromes are still common, and the underlying mechanisms largely elusive. Glycoprotein (Gp) Ia/IIa is one of several collagen receptors involved in platelet adhesion. A C807T gene variant of GpIa is related to Gp Ia/IIa receptor density on the platelet surface, with the density proportionate to the number of T all...

AIMS To assess the effects of pravastatin on all-cause mortality and cause-specific mortality and to compare the effects for patients with prior coronary heart disease with those for patients without, using pooled data from the Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) study, the Cholesterol and Recurrent Events (CARE) study, and the West of Scotland Coronary Preventi...

We encountered a 52-year-old man with Takayasu's disease (pulseless disease) and severe respiratory failure due to recurrent pulmonary hemorrhage. Angiography revealed occlusion of multiple branches of the pulmonary artery, which were filled via collateral circulation from the coronary, intercostal, and intermammary arteries. This is a rare case that causes massive pulmonary bleeding and respir...

background: coronary disease is the most common cause of death in the world. because of common risk factors, atherosclerotic stenosis of coronary and carotid arteries occurs together. this study evaluated the prevalence of carotid stenosis in diabetic candidates for angiography methods: in a cross-sectional study, 152 diabetic candidates for angiography referred to cardiology clinic of shariati...

conclusions cabg may be the superior form of treatment for long-term outcomes in terms of the relief of chest pain, improvement of the functional class, reduced need for re-admission, and later death for octogenarians. however, short-term morbidity may be higher among the cabg group, but the mortality rate after 30 days is quite similar. background appropriate treatment methods lead to a reduce...

background: obstructive sleep apnea (osa) is very frequent and often unrecognized in surgical patients. osa is associated with perioperative complications. we evaluated the effects of osa on postoperative complications and hospital outcomes in patients undergoing coronary artery bypass graft (cabg) surgery. methods: candidates of elective cabg were evaluated by the berlin questionnaire for osa....

Antiplatelet therapy with aspirin is a cornerstone of secondary prevention in coronary artery disease (CAD), mainly to prevent recurrent ischemic events. Specifically, it is recommended to use aspirin indefinitely in all revascularized patients.1,2 This “secondary preventive effect” of antiplatelet therapy is even more important in patients at high risk, such as those with acute coronary syndro...

BACKGROUND Interventional treatment improves prognosis in patients with acute coronary syndromes (ACS). However, despite introduction of percutaneous coronary intervention (PCI), the risk of cardiovascular events in patients with multivessel coronary artery disease (MVD) remains significant. AIM To evaluate the risk of complications and the prognostic value of MVD in patients with ACS during ...

Patients with multivessel coronary artery disease are more likely to have extensive atherosclerosis that involves other major arteries. Critical subclavian artery (SCA) stenosis can result in coronary subclavian steal syndrome that may present as recurrent ischemia and even myocardial infarction in patients with coronary artery bypass graft (CABG). In patients with concomitant severe native cor...