AIM To review the scientific publications concerning the clinical use and mechanism of action of the North American cranberry (Vaccinium macrocarpon) for women with recurrent urinary tract infections (UTI) and other health conditions. METHODS This is a retrospective study of published information concerning Vaccinium macrocarpon retrieved from a PubMed and individual searches. RESULTS Urina...

OBJECTIVE To determine the frequency of E. coli resistance to ciprofloxacin and common factors leading to it among patients presenting with urinary tract infection. STUDY DESIGN Descriptive cross-sectional study. PLACE AND DURATION OF STUDY Department of Medicine, Ayub Teaching Hospital, Abbottabad, from December 2011 to June 2012. METHODOLOGY A total of 166 patients, > 18 years of age of...

The interest in urinary tract infections (UTI) and vesicoureteral reflux (VUR), which is the retrograde flow of urine from the bladder into the ureter, started gaining pace in the late 1950s after the introduction of voiding cystourethrography. 1 VUR is present in one third of children presenting with febrile urinary tract infections (UTI) and is associated with renal scarring. 1 In an effort t...

microbial culture of urine. The dip stick method used in many centres serves only as a screening method but culture is needed for final diagnosis7. In almost all cases of nosocomial UTI, there is a need to start treatment before the final microbiological results are available. knowledge about the types of pathogens responsible for UTIs and their resistance pattern may help the clinician to choo...

To differentiate between relapse of infection and reinfection of the urinary tract due to Klebsiella pneumoniae, 33 K. pneumoniae isolates collected from 20 patients with spinal cord injury (SCI) over 2 years were typed by genomic fingerprinting by repetitive-element PCR. Clinical isolates obtained from the same patients with recurrent episodes of urinary tract infection (UTI) revealed identica...

Evidence Two 2012 systematic reviews1,2 and 1 RCT,3 all with about 6 months’ follow-up. • Cochrane review: 24 RCTs (13 RCTs with juice or concentrate, 10 with tablets or capsules, and 1 with both) of 4473 mostly female patients.1 -Meta-analysis of 13 RCTs found —no significant difference in number of patients getting 1 or more UTIs (relative risk [RR] = 0.86, 95% CI 0.71 to 1.04); and —no diffe...

BACKGROUND Urinary tract infections (UTIs) are commonly reported by people with multiple sclerosis (PwMS) and significantly impact quality of life. OBJECTIVE To provide an overview of the problem of UTIs in PwMS and offer a practical approach for the diagnosis and management. METHODS A review of the literature through a Pubmed search up to October 2015 was performed using the following keyw...

Data included in the meta-analyses (Fig. 1) showed that, compared with placebo, water or no treatment, cranberry products did not significantly reduce the occurrence of symptomatic urinary tract infection (UTI) overall (RR 0.86, 95% CI 0.71–1.04) or for any of the subgroups: women with recurrent UTI (RR 0.74, 95% CI 0.42–1.31); older people (RR 0.75, 95% CI 0.39–1.44); pregnant women (RR 1.04, ...

Urinary tract infections (UTIs) cause patient morbidity and have a substantial economic impact. Half of all women will suffer a UTI at least once, and 25% of these women will have recurrent infections. That 75% of previously infected women do not become reinfected strongly suggests a role for an adaptive immune response. The goal of this study was to characterize the adaptive immune responses t...

We report on a new Actinobaculum species, "Actinobaculum massiliae," isolated from the urine of an elderly woman with recurrent cystitis. Its phenotypic pattern was similar to those of both of the other Actinobaculum species described to date. On 16S rRNA sequencing, the Marseille isolate shared 95% homology with Actinobaculum suis, 92 to 93% homology with Actinobaculum schaalii, 91 to 92% homo...