In 1995, the WHO Global Programme for Vaccines and Immunization established a Vaccine Trial Registry. As of September 1996, this registry included 50 WHO-supported vaccine trials, of which 25 (50%) were completed studies. The vaccines most frequently tested have been against measles (9 trials), poliovirus (8 trials), cholera (8 trials), enterotoxigenic Escherichia coli (4 trials), and pneumococ...

OBJECTIVE To determine the age, sex and relative frequencies of various gastrointestinal malignancies in patients registered with the National Cancer Registry from the Western Region of Saudi Arabia from January 1994 till December 1997, and compare this data with previous hospital based studies about the pattern of these malignancies in Saudi Arabia. METHODS A National Cancer Registry was est...

In cancer epidemiology, prospective approaches are very important both in testing etiological hypotheses and in evaluating preventive procedures. Prospective studies, however, are very difficult and expensive, because a large number of people and a long period of observation are necessary for a satisfactory study. As a data source for follow-up studies, population-based cancer registry is very ...

BACKGROUND There is little information about congenital heart surgery outcomes in developing countries. The International Quality Improvement Collaborative for Congenital Heart Surgery in Developing World Countries uses a registry and quality improvement strategies with nongovernmental organization reinforcement to reduce mortality. Registry data were used to evaluate impact. METHODS Twenty-e...

OBJECTIVE To report the results of the first 1,132 subjects in a pilot project where local central nervous system trial sites collaborated in the use of a subject database to identify potential duplicate subjects. METHOD Central nervous system sites in Los Angeles and Orange County, California, were contacted by the lead author to seek participation in the project. CTSdatabase, a central nerv...

We have developed a model for clinical information routing within an immunization registry. Components in this model include partners, contents and mechanisms. Partners are classified into senders, receivers and intermediates. Contents are classified into core contents and management information. Mechanisms are classified into topological control, temporal control, process control and communica...

BACKGROUND The growing penetration of mechanical reperfusion in ST-elevation myocardial infarction (STEMI) has been achieved by the creation of new percutaneous coronary intervention (PCI) centres which have helped to shorten delays but have compromised PCI volumes. AIM To compare the outcomes in STEMI patients treated in PCI centres with or without surgical back-up. METHODS Data concerning...

background and objectives: survival models are statistical technique to estimate or predict the overall time up to specific events. prediction is important in medical science and the accuracy of prediction is determined by a measurement, generally based on loss functions, called prediction error. the aim of this study is using parametric models to determine the factors influencing predicted sur...

Abstract Vigabatrin is the medication used for treatment of infantile spasms and refractory complex partial seizures, but its usage has always been contradictory due to effect on vision. This review focuses registry, mechanism injury, animal study, pharmacokinetics, risk factors, efficacy, safety precautions vigabatrin. The first visual defect with vigabatrin use was detected in 1997. led initi...