We propose a novel hierarchical hidden Markov regression model for determining gene regulatory networks from genomic sequence and temporally collected gene expression microarray data. The statistical challenge is to simultaneously determine the groupings of genes and subsets of motifs involved in their regulation, when the groupings may vary over time, and a large number of potential regulators...

Wang Liang (Department of Control Science and Control Engineering, Huazhong University of Science and Technology, WuHan, 430074, P.R.China, E-mail: [email protected]) [Abstract] Climate modification measures to counteract global warming receive some more new attentions in these years. Most current researches only discuss the impact of these measures to climate, but how to design such a clima...

A mutant producing very high levels of the acetamidase enzyme encoded by the amdS gene has been isolated in a strain containing the amdA7 mutation, which itself causes high levels of this enzyme. Genetic analysis has shown that this mutation, designated amdI66, is adjacent to the amdS gene and is cis-dominant in its effect. The amdI66 mutation has little effect on amdS expression when present i...

Avhandlingen baseras på följande arbeten: I Rung JP, Carlsson A, Rydén Markinhuhta K, Carlsson ML (2005) (+)-MK-801 induced social withdrawal in rats; a model for negative symptoms of schizophrenia. Carlsson ML (2007) Effects of (-)-OSU6162 and ACR16 on motor activity in rats, indicating a unique mechanism of dopaminergic stabilization (submitted). The dopaminergic stabilizers (-)-OSU6162 and A...

In this article we propose a new algorithm for time synchronization in wireless sensor networks. The algorithm is based on linear regression to achieve long-term synchronization between the clocks of different network motes. Since motes are built using low-cost hardware components, usually their internal local clocks are not very accurate. In addition, there are other effects that affect the cl...

For many years, the importance of active feedback control of large space structure (LSS) have been widely recognized. This paper presents results on studying the attitude control problem for an LSS typified by the ETSVI (Engineering Test Satellite-VI) spececraft. The attitude control system based on the statefeedback control is proposed. The control law is designed by using the turn over design...

The Sgs-7 and Sgs-8 glue genes at 68C are divergently transcribed and are separated by 475 bp. Fusion genes with Adh or lacZ coding sequences were constructed, and the expression of these genes, with different amounts of upstream sequences present, was tested by a transient expression procedure and by germ line transformation. A cis-acting element for both genes is located asymmetrically in the...

The transition from vegetative to reproductive development is a central event in the plant life cycle. To time the induction of flowering correctly, plants integrate environmental and endogenous signals such as photoperiod, temperature and hormonal status. The hormone gibberellic acid (GA) has long been known to regulate flowering. However, the spatial contribution of GA signaling in flowering ...

This corrects the article DOI: 10.1038/srep45235.