lymphomas are classified as hodgkin’s and non-hodgkin’s lymphomas (hl nhl) nhl being further sub-divided into b, t and null cell categories on the basis of who classification. with a few exceptions worldwide, b-nhl are more common, accounting approximately 80-85% of all cases of nhl compared to t-nhl, which accounts for about 10-15% of all nhl cases. the incidence of nhl has shown a steady incr...

background and objectives: classic hodgkin lymphoma (chl), anaplastic large cell lymphoma (alcl) and some cases of diffuse large b cell lymphoma (dlbcl) have overlapping morphologic features. since they all represent distinct clinico-pathologic entities, we explored the differential diagnostic impact of immunophenotyping to discriminate between them. materials and methods: we included 61 cases ...

BACKGROUND Autologous or allogeneic hematopoietic stem cell transplant (SCT) is often considered in patients with relapsed or refractory non-Hodgkin lymphoma (NHL) but there are limited data on the use of SCT for the treatment of NHL in the pediatric setting. PROCEDURE To evaluate the role of SCT for children with NHL, we reviewed 36 consecutive pediatric patients with NHL who underwent an al...

The treatment of patients with relapsed and refractory Hodgkin lymphoma (HL), especially those who relapse after autologous stem cell transplantation, remains challenging. Patients with HL whose disease relapses after stem cell transplantation are rarely cured with current treatment modalities, and have a median survival of less than 3 years. Since no new drugs have been approved by the FDA for...

Relapsed or refractory Hodgkin lymphoma is a challenging problem for clinicians who treat hematologic malignancies. The standard management of these patients should include the use of salvage chemotherapy followed by autologous stem cell transplant (ASCT) in patients who are chemotherapy sensitive. Open issues in this area include the role of functional imaging, the specific chemotherapy regime...

To cite: Gupta A, Li HC. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2016-216343 DESCRIPTION Awoman in her 40s with relapsed follicular lymphoma presented with a few days history of shortness of breath and cough producing yellow sputum. There were no reported toxic exposures or contacts with sick people. Medications included idelalisib initiated 5 months ago ...

primary pancreatic lymphoma is a rare extranodal manifestation of any histopathologic subtype of b cell non-hodgkin's lymphoma that predominantly involves the pancreas. it comprises less than 0.2% of pancreatic malignancies and less than 0.7% of non-hodgkin's lymphomas. this lymphoma is almost never suspected clinically. it is usually diagnosed by surgical exploration for suspected ad...

Primary immunodeficiencies (PID) are genetically determined irreversible disorders of structure and/or functions the immune system's cellular and humoral components, accompanied by frequent infectious diseases contributing to development malignant neoplasms. Lymphomas most oncological disease in PID patients: non-Hodgkin's lymphomas occur 60 % neoplasms cases, Hodgkin lymphoma - 20 %, leukemias...

Treatment for childhood and adolescent non-Hodgkin lymphoma (NHL) has been optimised within the major biological subgroups for the last 30 years. Event-free survival rates reach almost 90% for mature B-cell NHL (B-NHL), 80% for lymphoblastic lymphomas (LBL) and 70% for anaplastic large cell lymphomas (ALCL). The efficacy of the front-line treatment leaves highly refractory relapsed disease, and...

constrictive pericarditis (cp) is an uncommon post inflammatory disorder. it is described as pericardial thickening, myocardial constriction, and impaired diastolic filling. the most common etiologies are idiopathy, mediastinal radiotherapy, and prior cardiac surgery. less common etiologies include viral infections, collagen vascular disorders, renal failure, sarcoidosis, tuberculosis, and blun...