Intraoperative radiotherapy differs from conventional, fractionated radiotherapy in several aspects that may influence its biological effect. The radiation quality influences the relative biologic effectiveness (RBE), and the role of the five R's of radiotherapy (reassortment, repair, reoxygenation, repopulation, radiosensitivity) is different. Furthermore, putative special biological effects a...

The present study was undertaken to determine relative biological effectiveness (RBE) values for simulated solar particle event (SPE) radiation on peripheral blood cells using Yucatan minipigs and electron-simulated SPE as the reference radiation. The results demonstrated a generally downward trend in the RBE values with increasing doses of simulated SPE radiation for leukocytes in the irradiat...

Considerable controversy currently exists regarding the biological effectiveness of 29 kVp X rays which are used for mammography screening. This issue must be resolved to enable proper evaluation of radiation risks from breast screening. Here a definitive assessment of the biological effectiveness of 29 kVp X rays compared to the quality of radiation to which the atomic bomb survivors were expo...

It is now well-established that outcomes of radiotherapy depend on quality of radiation. A large body of experimental evidences suggests that high-LET (linear energy transfer) radiation or particle radiation has the ability to kill tumor cells more efficiently than low-LET photon beams such as X-rays and γ-rays [1,2]. The unique characteristics of particle beam, which includes precise dose dist...

The objective of microdosimetry was, and still is, to identify physical descriptions of the initial physical processes of ionising radiation interacting with biological matter which correlate with observed radiobiological effects with a view to improve the understanding of radiobiological mechanisms and effects. The introduction of therapy with particles starting with fast neutrons followed by ...

An ad hoc model of energetic heavy ion beams, including secondary and tertiary particles, has been constructed for predicting radiobiological experiments. While the beam model is relatively primitive, it yields depth-dose and depth-radiobiological calculations in good agreement with experiment upstream of the Bragg peak. Beyond the peak, the model is somewhat coarse grained and seems to underes...

The risk of internal exposure to 137Cs, 134Cs, and 131I is of great public concern after the accident at the Fukushima-Daiichi nuclear power plant. The relative biological effectiveness (RBE, defined herein as effectiveness of internal exposure relative to the external exposure to γ-rays) is occasionally believed to be much greater than unity due to insufficient discussions on the difference of...

The transfer of spin angular momentum to a nanomagnet from a spin polarized current provides an efficient means of controlling the magnetization direction in nanomagnets. A unique consequence of this spin torque is that the spontaneous oscillations of the magnetization can be induced by applying a combination of a dc bias current and a magnetic field. Here we experimentally demonstrate a differ...

Yu-xi Liu, L. F. Wei, and Franco Nori Frontier Research System, The Institute of Physical and Chemical Research (RIKEN), Wako-shi 351-0198, Japan Institute of Quantum Optics and Quantum Information, Department of Physics, Shanghai Jiaotong University, Shanghai 200030, China Center for Theoretical Physics, Physics Department, Center for the Study of Complex Systems, The University of Michigan, A...

A microwave domain characterization approach is proposed to determine the properties of high quality factor optical resonators. This approach features a very high precision in frequency and aims to acquire a full knowledge of the complex transfer function (amplitude and phase) characterizing an optical resonator using a microwave vector network analyzer. It is able to discriminate between the d...