We previously showed that tumor necrosis factor-α (TNF-α) induces the dysregulation of intracellular calcium [Ca(2+)](i) in β-cells by decreasing the levels of the cytoplasmic Ca(2+) binding protein calbindin-D(28k). The purpose of the present study was to test the hypothesis that TNF-α-induced dysregulation of [Ca(2+)](i) in insulin-producing β-cells causes proteolytic degradation of IκBα and ...

noise removal operation is commonly applied as pre-processing step before subsequent image processing tasks due to the occurrence of noise during acquisition or transmission process. a common problem in imaging systems by using cmos or ccd sensors is appearance of  the salt and pepper noise. this paper presents cellular automata (ca) framework for noise removal of distorted image by the salt an...

In order to explore the possible mechanisms by which ethologically relevant sounds can be extracted from complex auditory environments, this study examined the effects of weak noise on the rate-intensity functions (RIFs) of neurons responding to tone burst in the inferior colliculus (IC) of nine mice (Mus musculus Km). Under free field stimuli conditions, a total of 112 IC neurons were recorded...

MADS-box genes have been reported to play a major role in the molecular circuit of developmental regulation. Especially, SEPALLATA (SEP) group genes play a central role in the developmental regulation of ripening in both climacteric and non-climacteric fruits. However, the mechanisms underlying the regulation of SEP genes to non-climacteric fruits ripening are still unclear. Here a SEP gene of ...

Tomato (Solanum lycopersicum) fruit ripening-specific N-glycan processing enzyme, β-D-N-acetylhexosaminidase (β-Hex), plays an important role in the ripening-associated fruit-softening process. However, the regulation of fruit ripening-specific expression of β-Hex is not well understood. We have identified and functionally characterized the fruit ripening-specific promoter of β-Hex and provided...

We experimentally analyze the impact of front-FBG reflectivity in ultra-long Raman laser amplifiers performance, showing Q-factor penalties in excess of 1 dB for FBG reflectivities above 10% in a 30 GBaud DP-QPSK transmission system. © 2016 OSA. DOCUMENT TYPE: Conference Paper 2. Impact of input FBG reflectivity and forward pump power on RIN transfer in ultralong Raman laser amplifiers (2016) O...

Dopaminergic signaling and plasticity are essential to numerous CNS functions and pathologies, including movement, cognition, and addiction. The amphetamine- and cocaine-sensitive dopamine (DA) transporter (DAT) tightly controls extracellular DA concentrations and half-life. DAT function and surface expression are not static but are dynamically modulated by membrane trafficking. We recently dem...