نتایج جستجو برای: releasing hormone agonists

تعداد نتایج: 196829  

2017
Hyo Kyoung Nam Hye Ryun Kim Young Jun Rhie Kee Hyoung Lee

Few studies have investigated the long-term effects of gonadotropin-releasing hormone (GnRH) agonist treatment on the reproductive function of central precocious puberty (CPP) girls. In this cross-sectional study, we assessed the ovarian function by analyzing the serum anti-Müllerian hormone (AMH) levels of CPP girls. Our study included 505 CPP girls subdivided into 5 groups according to the Gn...

Journal: :British journal of pharmacology 2016
Indira Nederpelt Victoria Georgi Felix Schiele Katrin Nowak-Reppel Amaury E Fernández-Montalván Adriaan P IJzerman Laura H Heitman

BACKGROUND AND PURPOSE Drug-target residence time is an important, yet often overlooked, parameter in drug discovery. Multiple studies have proposed an increased residence time to be beneficial for improved drug efficacy and/or longer duration of action. Currently, there are many drugs on the market targeting the gonadotropin-releasing hormone (GnRH) receptor for the treatment of hormone-depend...

Journal: :American journal of obstetrics and gynecology 2016
Linda D Bradley Ndeye-Aicha Gueye

In the treatment of women with abnormal uterine bleeding, once a thorough history, physical examination, and indicated imaging studies are performed and all significant structural causes are excluded, medical management is the first-line approach. Determining the acuity of the bleeding, the patient's medical history, assessing risk factors, and establishing a diagnosis will individualize their ...

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