objective(s):leptin receptor (lepr) is a member of the class i cytokine receptor super-family that is known implicated in the initiation and progression of breast cancer. we have investigated the effect of q223r polymorphism on the breast cancer susceptibly in a sample of iranian subjects. materials and methods:we utilized a polymerase chain reaction (pcr) restriction fragment length polymorphi...

Arzu, felsefeden psikolojiye, maddi kültür çalışmalarından sanat çalışmalarına kadar uzanan geniş bir alanda incelenen, üzerinde düşünülen olgudur. Edebiyat sahasında da incelenen arzu, özne-nesne ilişkisine dayalı anlatı türlerinde özneyi harekete geçiren itici güç işleviyle anlatının unsuru hâline gelir. Sözlü kültürden modern romana geleneğinin merkezinde yer alan bu güç, kahramanı arayışa, ...

In this paper, we propose a refinement of the modelling of biological regulatory networks based on the discrete approach of Rene Thomas. We refine and automatise the use of delays of activation/inhibition in order to specify which variable is more quickly affected by a change of its regulators. The formalism of linear hybrid automata is well suited to allow such refinement. We then use HyTech f...

The so-called leapfrog transformation that was first introduced for fullerenes (trivalent polyhedra with 12 pentagonal faces and all other faces hexagonal) is generalised to general polyhedra and maps on surfaces. All spherical polyhedra can be classified according to the i r leapfrog order. A polyhedron is said to be of Clar type if there exists a set of faces that cover each vertex exactly on...