نتایج جستجو برای: resequencing
تعداد نتایج: 2156 فیلتر نتایج به سال:
Aromatase [cytochrome P450 19 (CYP19)] is a critical enzyme for estrogen biosynthesis, and aromatase inhibitors are of increasing importance in the treatment of breast cancer. We set out to identify and characterize genetic polymorphisms in the aromatase gene, CYP19, as a step toward pharmacogenomic studies of aromatase inhibitors. Specifically, we "resequenced" all coding exons, all upstream u...
Genome-wide association studies (GWAS) have been used to identify regions of the genome related to various phenotypes in humans, corn, rice and cattle. Successful application of this approach to bioenergy crops such as Populus requires 1) an appropriate mapping population, 2) high-quality phenotypic data and 3) informative genotypic data. With the goal of reducing the recalcitrance of lignocell...
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