Sialylated recombinant human acetylcholinesterase (rHuAChE), produced by stably transfected cells, is composed of a mixed population of monomers, dimers and tetramers and manifests a time-dependent circulatory enrichment of the higher-order oligomeric forms. To investigate this phenomenon further, homogeneous preparations of rHuAChE differing in their oligomerization statuses were generated: (1...

We present a study of residence time statistics for N renewal processes with a long tailed distribution of the waiting time. Such processes describe many nonequilibrium systems ranging from the intensity of N blinking quantum dots to the residence time of N Brownian particles. With numerical simulations and exact calculations, we show sharp transitions for a critical number of degrees of freedo...

INTRODUCTION Rural residence may reduce access to specialized mental health services. The objective of this study was to examine the role of rural residence in relation to service utilization. Using Canadian data collected in 2002, service use was examined as a function of the presence of anxiety or mood disorders and rural/urban residence. Use of four different types of professional mental hea...

A method for estimation of mean baseflow residence time in watersheds from hydrograph runoff recession characteristics was developed. Runoff recession characteristics were computed for the period 1993–96 in the 2 km2 Winnisook watershed, Catskill Mountains, southeastern New York, and were used to derive mean values of subsurface hydraulic conductivity and the storage coefficient. These values w...

[1] Carbon residence time is one critical parameter for predicting future land carbon sink dynamics but has not been well quantified for many plant and soil pools. This study applied a probabilistic inverse analysis of multiple observations to estimate mean residence times of carbon among three forest ecosystems in eastern China. Three assimilation experiments were conducted with either net eco...

1. This study investigated the pharmacokinetics of thiamphenicol glycinate (TG) and thiamphenicol (TAP) in beagles (n = 6) after intravenous administration of 50 mg/kg TG hydrochloride. Plasma concentrations of TG and TAP were measured by a HPLC-UV method. 2. Two-compartment model was selected to describe the pharmacokinetic characteristics of TG and TAP in vivo. Main parameters were as follows...