Efficient designs are crucial for population genetic studies on forest species. In this study we employed individual based simulations aiming to evaluate what fraction of a population should be sampled to obtain confident estimations of allelic richness and of inbreeding coefficient in population genetic surveys. The simulations suggest that at least 10% of the total population has to be sample...

Synergistic epistasis for fitness is often assumed in models of how selection acts on the frequency and distribution of deleterious mutations. Evidence for synergistic epistasis would exist if the logarithm of fitness declines more quickly with number of deleterious mutations, than predicted by a linear decline. This can be studied indirectly by quantifying the effect of different levels of inb...

We describe a simple method to compute the numerator relationship between any or all pairs of animals in the numerator relationship matrix. The method depends on output of the MTDFNRM program from the MTDFREML set of programs. An option of the MTDFNRM program creates a file that includes the inbreeding coefficient for each animal. The method also makes use of how the inbreeding coefficient is t...

studbook information collected from 1988 to 2011 in jafarabad breeding station of moghani sheep, north-west of iran, related to 9,457 lambs were used to study the genetic diversity and to evaluate the effectiveness of an implemented rotational mating scheme using pedigree analysis. lambs born during 2009-2011 were considered as reference population. means inbreeding and average coancestry for t...

genetic values of independent lines with inbreeding have revealed large variability among lines (Bartual and HalThe average effects of inbreeding depression have been measured lauer, 1976; Cornelius and Dudley, 1974, 1976; Obilana extensively in maize (Zea mays L.), but the influence of inbreeding and Hallauer, 1974) and variability in inbreeding depreson genetic variance has not been well stud...

The statistical properties of the standardized variance of gene frequency changes (a quantity equivalent to Wright's inbreeding coefficient) in a random mating population are studied, and new formulae for estimating the effective population size are developed. The accuracy of the formulae depends on the ratio of sample size to effective size, the number of generations involved (t), and the numb...

It is shown that in a hierarchical island model, in which demes within a neighborhood exchange migrants at a much higher rate than do demes in different neighborhoods, hierarchical F statistics introduced by S. Wright can indicate the extent of gene flow within and between neighborhoods. At equilibrium, the within-neighborhood inbreeding coefficient, FSN, is approximately 1/(1 + 4Nm1) where N i...

Consanguineous marriages are strongly favoured among the populations of South India. In a study conducted on 407 infants and children, a total of 35 genetic diseases was diagnosed in 63 persons: 44 with single gene defects, 12 with polygenic disorders, and seven with Down's syndrome. The coefficient of inbreeding of the total study group, F = 0.0414, was significantly higher than that previousl...

Patterns of population genetic variation have frequently been understood as consequences of life history covariates such as dispersal ability and breeding systems (e.g. selfing). For example, marine invertebrates show enormous variation in life history traits that are correlated with the extent of gene flow between populations and the magnitude of differentiation among populations at neutral ge...