We performed a retrospective study of 164 human immunodeficiency virus (HIV)-infected patients with disseminated histoplasmosis to identify the risk factors for death. Death occurred in 32% of the cases. Univariate analysis identified the following risk factors: diarrhea (odds ratio [OR] = 3.9, P = 0.001), neurologic manifestations (OR = 5.8, ; P = 0.001), hemoglobin level < 8.0g/dL (OR = 2.7, ...

An 82-year-old female, with left femoral neck fracture was scheduled for left hip hemiarthroplasty, under spinal anaesthesia. She had been suffering from diabetes, hypertension, lung cancer and was previously treated with IV aminophylline for respiratory insufficiency. She was given spinal anaesthesia with 10 mg of 0.5% hyperbaric bupivacaine, and T6 sensory block level was established. After 1...

1. Schwarz K, Thwaites R, Minford A, Day C, Butler G. Congenital adrenal hypoplasia presenting as a chronic respiratory condition. Arch Dis Child 2003; 88: 261-262. 2. Watterberg KL, Scott SM, Backstrom C, Gifford KL, Cook KL. Links between early Congenital adrenal hypoplasia is rare with an incidence of 1 in 12,500 life births. Links between early adrenal insufficiency and adverse respiratory ...

Adrenal insufficiency is a potential complication of therapy with an inhaled corticosteroid (ICS). Although prior studies found the highest risk of adrenal insufficiency with fluticasone, a more potent ICS, these results might be explained by a channelling bias and concomitant exposure to oral corticosteroids. We re-examined the relationship between the use of ICSs and adrenal insufficiency by ...

adequately ventilate), or both hypoxic and hypercapnic. In addition, respiratory failure can be caused by an inability to protect the airway. Alterations in the normal physiology and anatomy of the respiratory system can lead to respiratory failure requiring mechanical ventilation. Anatomic alterations causing airway obstruction, such as tumors, edema, direct or indirect trauma, burns, or other...

This study assessed two 85-year-old patients diagnosed with diastolic heart failure and persistent respiratory insufficiency characterized by severe obstructive ventilatory disorder and gas exchange alterations. The possibility that the respiratory impairment was consequent to primary pulmonary disease was excluded. Radiological signs of mild pulmonary edema had been observed in 1 of the patien...

Childhood onset motor neuron diseases or neuronopathies are a clinically heterogeneous group of disorders. A particularly severe subgroup first described in 1894, and subsequently called Brown-Vialetto-Van Laere syndrome, is characterized by progressive pontobulbar palsy, sensorineural hearing loss and respiratory insufficiency. There has been no treatment for this progressive neurodegenerative...

PURPOSE To investigate dark adaptation during hypoxia in patients with chronic respiratory failure. METHODS At three visits, dark adaptation was recorded by computerized dark adaptometry in 13 patients with chronic respiratory insufficiency treated by long-term oxygen therapy. At visits 1 and 3, the patients were administered their usual oxygen supplement. At visit 2, no oxygen was given. At ...

The centronuclear myopathies (CNMs) are a group of inherited neuromuscular disorders classified as congenital myopathies. While several causative genes have been identified, some patients do not harbor any of the currently known mutations. These diverse disorders have common histological features, which include a high proportion of centrally nucleated muscle fibers, and clinical attributes of m...

) is among the most common rapidly Mycobacterium abscessus M. abscessus growing mycobacteria causing infections in humans. Skin and soft tissue infections, especially those following trauma or surgery are the most common infections caused by this pathogen. We describe the case of a 22-year old female with cerebral palsy and chronic respiratory insufficiency requiring nocturnal ventilation throu...