Ropinirole is a non-ergoline dopamine agonist that exhibits a high affinity for D(2) and D(3) receptors but little or no affinity for D(1)-like and non-dopaminergic receptors. Symptoms of restless legs syndrome (RLS) [measured using the International Restless Legs scale and Clinical Global Impression-Global Improvement Scale scores] significantly improved with ropinirole compared with placebo i...

dopamine agonists, particularly nonergot dopamine agonists such as pramipexole, have become the mainstay of therapy for patients with symptoms of restless legs syndrome (rls). this study was designed to evaluate the factors affecting the efficacy of pramipexole in patients with rls. fifty-nine eligible rls patients referred to neurology clinic of rasoul-e-akram hospital (tehran, iran) were recr...