نتایج جستجو برای: revised oci
تعداد نتایج: 55005 فیلتر نتایج به سال:
OBJECTIVE Recent studies have emphasized the important role of cognitive beliefs in etiology and maintenance of obsessive-compulsive disorder (OCD). OCD has different subtypes, but the specific role of cognitive beliefs in OCD symptomatology is not clear. The aim of the current study was to determine whether the cognitive factors proposed by Obsessive Compulsive Cognitions Working Group (OCCWG)...
type text or a website address or translate a document. abstract liquidity is considered the most important aspect of the development of stock markets. the main objective of this study was to evaluate the effect of the quality of financial information provided to replace its financial statements nmvdh and shrkt hayy that the liquidity of the shares on the tehran stock exchange is between the ...
The use of a spacemaximum likelihood (S-ML) detection scheme is known to be optimum tomitigate other-cell interference (OCI) near the cell boundary. However, it is not applicable mainly due to implementation complexity. To reduce the implementation complexity, we consider combined use of S-ML detection and minimum-mean-square-error based ordered successive interference cancellation (MMSE-OSIC) ...
The effect of recombinant human interleukin-4 (IL-4) on a granulocyte colony-stimulating factor (G-CSF)-dependent human myeloblastic leukemic cell line, OCI-AML1a, was investigated. IL-4 suppressed the clonogenic cell growth in methylcellulose culture, inhibited the uptake of 3H thymidine in a dose-dependent manner at 5 to 100 U/mL, and consequently suppressed the growth of clonogenic cells in ...
Kit is a membrane-bound tyrosine kinase and receptor for stem cell factor (SCF) with a crucial role in hematopoiesis. Mutations of KIT occur in almost half of patients with core-binding factor leukemias, in which they have been associated with worse outcome. Development of new compounds targeting Kit may therefore hold promise for therapy. We investigated the activity and mechanism of action of...
BACKGROUND Both the multi-kinase inhibitor sorafenib and the small molecule inhibitor of the MDM2/p53 interaction, nutlin-3, used alone, have shown promising anti-leukemic activity in acute myeloid leukemia cells. Thus, in this study we investigated the effect of the combination of sorafenib plus nutlin-3 in acute myeloid leukemia. DESIGN AND METHODS Primary acute myeloid leukemia blasts (n=1...
PURPOSE We determined the effects of vorinostat (suberoylanalide hydroxamic acid) and/or MK-0457 (VX-680), an Aurora kinase inhibitor on the cultured human (HL-60, OCI-AML3, and K562) and primary acute myelogenous leukemia (AML) and chronic myelogenous leukemia (CML), as well as on the murine pro-B BaF3 cells with ectopic expression of the unmutated and mutant forms of Bcr-Abl. EXPERIMENTAL D...
Interleukin-6 (IL-6) has been shown to stimulate the proliferation of multiple myeloma cells purified to a high degree from human bone marrow. IL-6 production in multiple myeloma has been attributed to cells belonging to the myeloma clone, thus supporting a mechanism of autostimulation. In addition, it has been shown that IL-6 may be produced by auxiliary cell populations of the bone marrow tha...
شایستگی شته سیب زمینی Macrosiphum euphorbiae)) و پارازیتوئید آن Aphidius nigripes)) روی پنج رقم گیاه سیب زمینی (ترانس ژنیک – BT‘ ترانس ژنیک – OCI ‘ کلاسیک NYL 235-4 و دو شاهد) با درجات و مکانیسم های مختلف مقاومت به سوسک کلرادو Leptinotarsa decemlineata)) در شرایط آزمایشگاهی مورد بررسی قرار گرفت. نتایج آزمایشگاهی نشان داد که عوامل مقاومت به سوسک کلرادو به اشکال مختلف بر زیست شناسی شته سیب زمینی...
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