Background: Autoimmune disorders (AID) are emerging non-communicable diseases and understanding their epidemiology could reveal information about their clinical characteristics and disease management. Objective: To record the different types of arthritis cases attending a tertiary care center and study the profile of rheumatoid arthritis cases. Methods: The different types of arthritis cases re...

Rheumatoid arthritis (RA) is a chronic systemic disease of unknown etiology characterized by articular involvement, extra-articular involvement, and the presence of serum rheumatoid factor. Pulmonary involvement in RA is a common extra-articular manifestation of rheumatoid arthritis (RA) that confers significant morbidity and mortality. We undertook this study to determine the prevalence and sp...

Background: Rheumatoid Arthritis (RA) is a crippling disorder with articular, extra-articular as well systemic drawbacks. The present study was conducted to assess disease activity score respect vitamin D in rheumatoid arthritis. Materials & Methods: 58 patients of arthritis both genders were selected and measurement done ELISA an autoanalyzer. Disease 28 (DAS28) Visual analog scale scoring sys...

The presence of anergy and its relationship to malnutrition was investigated in patients with rheumatoid arthritis (RA) and in controls. A generalised reduction in delayed cutaneous hypersensitivity to 7 recall antigens were found in 104 RA patients compared with 67 controls. No measured of the disease was capable of predicting cutaneous anergy, which was present in 36% of patients but none of ...

A collection of synovial fibroblasts from 19 patients with rheumatoid arthritis (RA) and 12 patients with osteoarthrosis or other non-RA disease has been examined for rubella virus antigens by immunofluorescence and radioimmunoassay with negative results. Eluates of synovial membrane prepared under conditions likely to dissociate antigen-antibody complexes have shown no rubella antibody. A sero...

Burden of rheumatoid arthritis Rheumatoid arthritis (RA) is a chronic inflammatory disease, which is characterized by erosion of cartilage and bone. The underlying cause of RA is not fully understood but it is considered to be an autoimmune disease. RA has a prevalence of 0.5–1% worldwide. A study reporting RA duration, of time from onset until work disability, found that 10% of patients stoppe...

background: single-nucleotide polymorphism (snp) rs2476601 within protein tyrosine phosphatase non-receptor type 22 gene (ptpn22) has been shown to be a risk factor for different autoimmune diseases. this study explored the association of 1858 c/t snp with rheumatoid arthritis (ra) and celiac disease (cd) in a region covering south-west of iran. methods: totally, 52 patients with cd, 120 patien...

Introduction Familial Mediterranean fever (FMF) is an autosomal recessive disease that is prevalent among eastern Mediterranean populations, mainly non-Ashkenazi Jews, Armenians, Turks, and Arabs. Arthritis seen in FMF patients is generally acute monoarthritis which predominantly affecting the lower limbs, and it occurs during attack periods and also is a common clinical manifestation in patien...

A SAMPLING of 49 family clusters consisting of a key person with arthritis, his (her) spouse, a sibling and the sibling’s spouse, 2 cousins, and an unrelated individual were interviewed three times with regard to their arthritis and a variety of social and psychological factors. The sample was drawn in part from a national random sample and in part from an arthritis clinic. A detailed interview...

UNLABELLED Rheumatoid arthritis (RA) is the most common inflammatory rheumatic disease, affecting almost 1% of the world population. Although the cause of RA remains unknown, the complex interaction between immune mediators (cytokines and effector cells) is responsible for the joint damage that begins at the synovial membrane. Activated macrophages are critical in the pathogenesis of RA and sho...