This study was performed to define further the relationship of circulating IgM and IgG rheumatoid factor to the articular manifestations of rheumatoid arthritis. Patients with substantial clinical improvement (greater than 55%) or no improvement or worsening were chosen for study. Patients were further selected to include those treated with non-steroidal anti-inflammatory drugs (NSAIDs) alone, ...

Introduction: For the diagnosis of Rheumatoid Arthritis (RA), detection autoantibodies, rheumatoid factor (FR) and cyclic citrullinated peptide antibodies (APCC) are used. The presence these determines that RA is classified as seropositive or seronegative, with important implications both in clinical development prognosis disease. Objective: To assess role APCC RF RA, well its influence on esta...