PURPOSE Iron overload may occur due to regular blood transfusions and high intestinal iron absorption. Currently, there is no effective drug without side effects for the treatment of iron excess in thalassemia and other iron storage diseases, except chelation therapy, which is the only safe method for iron excretion. Thus, scientists are more focused on medicinal plants rich in phytochemical co...

objective: inflammation and oxidative stress is considered to have a crucial role in induction of nephropathy. curcuma longa (c. longa) and nigella sativa (n. sativa) have anti-inflammatory and antioxidant effects. this study was designed to investigate the effect of mixed hydro-alcoholic extract of n.sativa and c. longa on the oxidative stress induced by adriamycin (adr) in rat kidney. materia...

background: the science of identification and employment of medicinal plants dates ‎back to the early days of man on earth. cannabis (hashish) is the most common illegal ‎substance used in the united states and was subjected to extensive research as a ‎powerful local disinfecting agent for mouth cavity and skin and an anti-tubercular agent ‎in 1950.‎ methods: clinical strains were isolated from...

The alcoholic extract of Guazuma ulmifolia was evaluated for their wound healing activity in Albino Wistar rats using chemically induced wound model. The experimental animals were chemically burned by conc HCL (80%), and then divided into four groups, control, standard (Nitrofurazone 0.2% w/w), low dose (125 mg/kg) and high dose (250mg/kg). The reepithelialization was evaluated by the reducing ...

objective: the present study was conducted to investigate the hepatoprotective activity of hydro-ethanolic fruit extract of rosa canina (r. canina) against carbon tetrachloride (ccl4)-induced hepatotoxicity in rats. methods: male wistar albino rats were randomly divided into six groups of 8 animals of each, including control, toxic (ccl4), r. canina 250, 500, and 750 mg/kg + ccl4 and r. canina ...

Ferula gummosa Boiss is a good source of biologically active compounds such as monoterpene and sesquiterpene derivatives. There are also several reports on antioxidant effects of these compounds. The aim of this study was to investigate the effect of daily administration of F. gummosa root hydro-alcoholic extract on serum oxidant-antioxidant status. Twenty four Wistar rats were randomly divided...

Active packaging based on chitosan (Ch) incorporated with six different natural hydro-alcoholic extracts (HAE) (rosemary, green tea, black ginger, kenaf, and sage) were developed tested to extend the shelf life of fresh poultry meat. The quality meat packaged was assessed through physical-chemical microbiological characterization over 15 days refrigerated storage. In vitro antimicrobial activit...

background and purpose: gentamicin-induced nephrotoxicity results from the production of reactive oxygen species (ros) in the kidneys, and since cinnamon has antioxidant properties, this research studied the effects of cinnamon extract on the prevention and treatment of gentamicin-induced toxicity in immature white rats.materials and methodology: in this study 36 immature female wistar rats wer...

This study investigated the cytotoxic activity of Rosmarinus officinalis L. (rosemary) aqueous extract on the cell cycle of Allium cepa. To this end, crude aqueous leaf extracts at four concentrations, 0.02, 0.04, 0.06 and 0.08 mg/mL, were tested on A. cepa meristematic root cells, at exposure times of 24 and 48 h. Slides were prepared by the crushing technique, and cells analyzed throughout th...