Little is known about the fundamental biology of parasitic nematodes (=roundworms) that cause serious diseases, affecting literally billions of animals and humans worldwide. Unlocking the biology of these neglected pathogens using modern technologies will yield crucial and profound knowledge of their molecular biology, and could lead to new treatment and control strategies. Supported by studies...

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The clinical spectrum of human disease caused by the roundworms Toxocara canis and Toxocara cati ranges from visceral and ocular larva migrans to covert toxocariasis. The parasite is not typically recovered in affected tissues, so detection of parasite-specific antibodies is usually necessary for establishing a diagnosis. The most reliable immunodiagnostic methods use the Toxocara excretory-sec...

Toxocara spp., the common roundworms of domestic and wild animals, are the causative agents of larval toxocarosis in humans. The migration of Toxocara larvae in men causes clinical syndrome, called larva migrans visceralis or larva migrans ocularis. The objective of the present work was to investigate the prevalence of toxocarosis in dogs, red foxes (Vulpes vulpes), and small mammals in the Slo...

Euclea natalensis is traditionally used as herbal medicine for several human diseases and ailments in tropical Africa. This study reviews information on ethnomedicinal uses, botany, phytochemical constituents, pharmacology and toxicity of E. natalensis. Results of this study are based on literature search from several sources including electronic databases, books, book chapters, websites, these...

Cyst nematodes are plant-parasitic roundworms that are of significance in many cropping systems around the world. Cyst nematode infection is facilitated by effector proteins secreted from the nematode into the plant host. The cDNAs of the 25A01-like effector family are novel sequences that were isolated from the oesophageal gland cells of the soybean cyst nematode (Heterodera glycines). To aid ...

Plant parasitic nematodes are microscopic roundworms which live in the soil and attack the roots of plants. Crop production problems induced by nematodes therefore generally occur as a result of root dysfunction, reducing rooting volume and foraging and utilization efficiency of water and nutrients. Many different genera and species of nematodes can be important to crop production in Florida. I...

Introduction Roundworms of the genus Trichinella are spread worldwide and are responsible for one of the most serious helminthic zoonoses. It is recognized that in many parts of the world none of the existing methods of control for Trichinella infection are applied because of the economic problems, erosions of veterinary infrastructures, failure of educational systems, ineffective abattoir cont...

WHILE SHEEP, like other farm animals, suffer from various infectious and noiiinfectious diseases, the most serious losses, especially in farm flocks, are due to internal parasites. These losses result not so much from deaths from gross parasitism, although fatalities are not infrequent, as from loss of condition, unthriftiness, anemia, and other effects. Devastating and spectacular losses, such...

Intestinal nematodes or roundworms (aka soil-transmitted helminths or STHs) cause great disease. They infect upwards of two billion people, leading to high morbidity and a range of health problems, especially in infected children and pregnant women. Development of resistance to the two main classes of drugs used to treat intestinal nematode infections of humans has been reported. To fight STH i...