Just before 9 a.m. on March 15, Danica Lomeli, 28, a soon-to-be MD, stood huddled with a crowd of family members, waiting to open the white envelope gripped in her shaking hands. Her mom, dad, brother, cousins and best friend glanced curiously at the envelope that would play an important role in shaping Lomeli’s future — the result of years of hard work and sacrifice in her quest to become a fa...

We study two combinatorial parameters, which we denote by f(S) and h(S), associated with an arbitrary set S ⊆ Rd, where d ∈ N. In the nondegenerate situation, f(S) is the largest possible number of facets of a d-dimensional polyhedron L such that the interior of L is disjoint with S and L is inclusion-maximal with respect to this property. The parameter h(S) is the Helly number of the family of...

For any g > 2 we construct a graph Γg ⊂ S whose exteriorMg = S\N(Γg) supports a complete finite-volume hyperbolic structure with one toric cusp and a connected geodesic boundary of genus g. We compute the canonical decomposition and the isometry group of Mg, showing in particular that any selfhomeomorphism of Mg extends to a self-homeomorphism of the pair (S ,Γg), and that Γg is chiral. Buildin...

Health[1] Health[1]Bacteria [2]Children's health [3]illness [4]immune system [5]Stress [6]Viruses [7]Norway [8] Forskning.no [9] High levels of stress in a family can undermine a child?s immune system, making it easier for viruses and bacteria to do their worst. Our immune system protects us from bacteria and viruses. But intense or long-lasting psychological stress can have a negative effect o...

1608–9 was a difficult year for James I of England as a monarch and as a father. His triumphal 1603 progress through England and the providentially thwarted threat of Gunpowder Plot in 1605 had lost their power to generate automatic goodwill for his domestic and foreign policies. The 1607 Parliament had been a disaster for James, refusing to pass his plan to create a ‘Great Marriage’ between Sc...

S-acylation is a reversible lipid modification occurring on cysteine residues mediated by a family of membrane-bound 'zDHHC' enzymes. S-acylation predominantly results in anchoring of soluble proteins to membrane compartments or in the trafficking of membrane proteins to different compartments. Recent work has shown that although S-acylation of some proteins may involve very weak interactions w...