background: in cancers of prostate, breast, oropharynx, lung, hypopharynx and skin, human tissue kallikreins has been demonstrated as a main role in these problems. there are many research works in which some human tissue kallikreins are expressed in salivary glands. in the present study, the main goal was to determine expression of human tissue kallikreins 4, 8, 10, 11 and 13 in pleomorphic ad...

BACKGROUND The prognosis of adenoid cystic carcinoma (ACC), a malignant salivary gland tumour, depends on clinicopathological parameters. To decipher the biological behaviour of ACC, and to identify patients at risk of developing metastases, additional markers are needed. METHODS Expression of the cell cycle proteins p53, cyclin D1, p16(INK4a), E2F1 and Ki-67, together with the Polycomb group...

The monitoring of the patients after salivary gland tumors surgery is an important clinical issue. Still imperfect diagnostic procedures also remain a challenge for searching new sensitive and specific biomarkers of neoplastic processes in salivary glands. The aim of the presented study was an the assessment of the activity of HEX, with its isoforms HEX-A and HEX-B, GLU, GAL, MAN and FUC in sal...

UNLABELLED Cancer of the salivary gland is one of the common cancers in the head and the neck regions. This type of cancer develops in the minor and the major salivary glands, and it sometimes metastasizes to other organs, particularly the lung. Morphologic mimicry and similarity in the expression of steroid hormone receptors between salivary gland tumours and breast tumours are well-known phen...

The salivary gland system consists of a network of major and minor secretory glands and ducts, that keep the oral cavity and upper aerodigestive tract moist and lubrificated; the oral salivary glands dissolve also water-soluble compounds and begin the digestion 1. They account for 6-8% of all tumours of the head and neck area, and the majority of them are benign and occur in the parotid gland. ...

BACKGROUND The characteristic cytologic features of the common salivary gland lesions have been well-delineated in literature. However, there also exist cytologic pitfalls and overlapping features that make an accurate diagnosis difficult in few cases. The present study was designed to compare the cytologic findings of salivary gland lesions with the histologic diagnoses, in order to assess the...

Introdouction: Mucoepidermoid carcinoma (MEC) is one of the most common salivary gland malignancies. The prevalence of salivary gland tumors varies in different geographic areas. In this report, we evaluated the prevalence of MEC in Iran and compared it with that previously reported in other countries. Materials and methods: The files of oral pathology, Shahid Beheshti University of Medical ...

salivary gland tumors are rare in children and, when they do arise, they mainly affect the major salivary glands. minor salivary gland tumors are rare in children and are responsible for less than 10% of the cases. pleomorphic adenoma is the most common tumor of the salivary glands. the most common sites of pleomorphic adenoma of the minor salivary glands are the palates, followed by the lips a...

introduction: chronic sclerosing sialadenitis is a relatively uncommon disorder of the salivary gland. because of its clinical similarity to a salivary gland neoplasm, this condition has been known as kuttner tumor and is classified as a tumorlike lesion. case report: this is the first reported case of bilateral kuttner tumor of the submandibular glands in iran. it was initially diagnosed as a ...