Abstract Aim Salvage Robot-Assisted Radical Prostatectomy (sRARP) is a potential treatment option for locally recurrent Prostate Cancer after non-surgical primary treatment. There are minimal data comparing outcomes between propensity-matched salvage and (RARP). We compare perioperative, oncological, functional of sRARP with RARP post-whole focal gland therapy. Method 1:1 comparison 146 from co...

STUDY TYPE Therapy (case series). LEVEL OF EVIDENCE 4. What's known on the subject? and What does the study add? Despite excellent surgical cancer control, up to 40% of patients will have biochemical recurrence following radical prostatectomy (RP) for localized prostate cancer. Positive surgical margins (PSM) have been clearly demonstrated to be one of the main predictive factors for biochemi...

A 62-year-old female was diagnosed with acute myeloid leukemia (AML) t(16;21)(p11;q22). She achieved complete hematological remission after induction therapy and underwent umbilical cord blood stem cell transplantation (CBT). At 150 days the CBT, a bone marrow examination revealed relapse. We treated patient venetoclax plus azacitidine as salvage therapy. After five cycles of therapy, died due ...

It has recently been reported that hepatitis B virus (HBV) reactivation in patients with hepatitis B surface antigen (HBsAg)-negative lymphoma during or after cytotoxic therapy occurs after the use of rituximab and stem cell transplantation for hematologic malignancies. However, clinical data on HBV reactivation in multiple myeloma patients have not been extensively reported. This is the first ...

Mucormycosis carries a high mortality rate with few therapeutic options available. We describe a man with pulmonary/splenic mucormycosis complicating hypoplastic myelodysplastic syndrome on a background of chronic kidney disease, who achieved a complete response with salvage isavuconazole therapy following intolerance of consecutive courses of liposomal amphotericin and posaconazole therapy.

A 68-year-old patient with severe biliary pancreatitis developed extensive retroperitoneal necroses, with air collections, extending from the pancreatic compartment to the pelvis (●" Fig.1a,b). Percutaneous and transgastric drainage (twice each) did not resolve the solid calcified infected material (vancomycin-resistant enterococci, Staphylococcus epidermidis, Neisseria subflava, Haemophilus in...

Summary: Background: This study aimed to evaluate the differences between outcomes of patients with intermittent claudication (IC) and chronic limb threatening ischemia (CLTI) who underwent a hybrid procedure comprising common femoral artery endarterectomy endovascular therapy. Patients methods: was retrospective single-center all peripheral arterial occlusive disease (PAD) March 2007 August 20...

Objectives: It is unclear as yet whether or not adjuvant treatment for radical prostatectomy achieves better oncologic results than early salvage treatment. Methods: Three recently published randomized clinical trials have shown that adjuvant radiation therapy (ART) for pT3 prostate cancer with or without positive surgical margins (PSMs) and seminal vesicle invasion (SVI) is associated with a 2...