Staphylococcus aureus is an Important agent of food poisoning. In many countries, it is the main bacterial organism responsible for diseases caused by exotoxin production and direct invasion with systemic dissemination. In poultry, S. aureus is associated with many clinical syndromes including tenosynovitis, omphalitis, femoral head necrosis, infected hock and stifle joints secondary to coccidi...

Vinculin, a 116-kDa membrane cytoskeletal protein, is an important molecule for cell adhesion; however, little is known about its other cellular functions. Here, we demonstrated that vinculin binds to Rab5 and is required for Staphylococcus aureus (S. aureus) uptake in cells. Viunculin directly bound to Rab5 and enhanced the activation of S. aureus uptake. Over-expression of active vinculin mut...

The appearance of methicillin-resistant Staphylococcus aureus (MRSA) as an endemic microbe, first in hospital and health care settings and more recently in the community, has led to a disastrous situation in which use of the available antibiotic armamentarium is increasingly ineffective and spawns further antibiotic resistance. This vicious cycle highlights the pressing need for an S. aureus va...

conclusions in our study, inducible clindamycin resistance rate was 4%; so it is necessary to conduct d-test regularly by disc diffusion for this bacterium. resistance to erythromycin, clindamycin, ciprofloxacin and gentamicin was significantly higher in mrsa isolates than methicillin susceptible staphylococcus aureus (mssa), although the methicillin resistance prevalence was low. background st...

there is a growing concern about the application of molecular methods in epidemiological studies of infectious diseases. the objective of this study was to determine the genetic stability of methicillin resistance genes in staphylococcus aureus for the evaluation of resistance strain distribution. one hundred and fifteen s. aureus isolates from patients with staphylococcal infection were collec...

conclusions methicillin-resistant staphylococcus aureus is an increasingly common cause of nosocomial infections. our results are in agreement with those of other studies reporting that a few specialized clones are responsible for most cases of mrsa nasal carriage. in this study, mrsa strains isolated from different wards of hospital were closely related when analyzed by coagulase gene typing. ...

BACKGROUND Central venous catheter-related infections are the most common cause of nosocomial S. aureus bacteraemia in Denmark. Central venous catheters are often used for dialysis, and patients on dialysis often run into staphylococcal infections. The purpose of this study was to investigate S. aureus bacteraemia among dialysis patients, especially those related to dialysis catheters. METHOD...

BACKGROUND The pathogenicity of staphylococcus aureus is dependent largely upon its ability to secrete a number of virulence factors, therefore, anti-virulence strategy to combat S. aureus-mediated infections is now gaining great interest. It is widely recognized that some plant essential oils could affect the production of staphylococcal exotoxins when used at subinhibitory concentrations. Per...

Dairy goat and sheep farms suffer severe economic losses due to intramammary infections, with Staphylococcus aureus representing the main cause of clinical mastitis in small ruminants. In addition, S. aureus contamination of goat and sheep milk may cause staphylococcal food poisoning, as many traditional caprine and ovine milk products are not subjected to pasteurization. Data on virulence and ...

BACKGROUND Staphylococci can cause wound infections and community- and nosocomial-acquired pneumonia, among a range of illnesses. Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) have been rapidly increasing as a cause of infections worldwide in recent decades. Numerous reports indicate that S. aureus and MRSA are becoming resistant to many antibiotics, which makes them very dan...