Introduction Traumatic Brain Injury (TBI) remains a leading cause of morbidity and disability and is considered a major public health concern. Ischemia is considered a relevant factor in TBI for prognosis, but its diagnosis in the early phases is still a problem. Now jugular venous oxygen saturation (SjVO2) is used to evaluate blood flow and cerebral metabolic rate as well as the cerebral venou...

We consider immiscible and incompressible two-phase flow in porous media under steady-state conditions using a dynamic pore network model. focus on the fluctuations Representative Elementary Area (REA), with aim to demonstrate that statistical distributions of volumetric rate saturation within REA become independent size entire model when is large enough. This independence necessary condition f...

We theoretically investigate the efficiency of initial binding between a receptor-coated sphere and a ligand-coated wall in linear shear flow. The mean first passage time for binding decreases monotonically with increasing shear rate. Above a saturation threshold of the order of a few 100 receptor patches, the binding efficiency is enhanced only weakly by increasing their number and size, but s...

BACKGROUND Mechanical ventilation via automated in-hospital ventilators is quite common during cardiopulmonary resuscitation. It is not known whether different inspiratory triggering sensitivity settings of ordinary ventilators have different effects on actual ventilation, gas exchange and hemodynamics during resuscitation. METHODS 18 pigs enrolled in this study were anaesthetized and intubat...

Various energy recovery, storage, conversion and environmental operations may involve repetitive fluid injection thus, cyclic drainage–imbibition processes. We conducted an experimental study for which polydimethylsiloxane (PDMS)-based micromodels were fabricated with three different levels of pore-space heterogeneity (coefficient variation, where COV = 0, 0.25 0.5) to represent consolidated an...

The effects of different parameters on the hydrodynamics of trickle bed reactors were discussed for Newtonian and non-Newtonian foaming systems. The varying parameters are varying liquid velocities, gas flow velocities and surface tension. The range for gas velocity is particularly large, thanks to the use of dense gas to simulate very high pressure conditions. This data bank has been used to c...

Sintering behavior with and without external stress was investigated using undoped and doped (1500 ppm yttria) sub-micron a-alumina powders. The yttria doped alumina showed anomalous behavior with grain size around 0.9 pm, a second peak in densification rate during free sintering and a stagnation followed by a steep increase in flow stress during sinter forging. These were thought to correspond...

Quantitatively determining physiological parameters at a microscopic level in the retina furthers the understanding of the molecular pathways of blinding diseases, such as diabetic retinopathy and glaucoma. An essential parameter, which has yet to be quantified noninvasively, is the retinal oxygen metabolic rate (rMRO2). Quantifying rMRO2 is challenging because two parameters, the blood flow ra...

Background/Purpose: The cerebral metabolic rate of oxygen consumption (CMRO2) is a fundamental physiologic parameter that has only recently become amenable to measurement by noninvasive imaging modalities (1). Here, we present an approach based on simultaneous quantification of venous oxygen saturation (SvO2) and total flow, yielding CMRO2 in absolute physiologic units by invoking Fick’s equati...