Abstract Common scab, calcium deficiency, and internal tuber defects, such as hollow heart, have severe negative impact on the marketable yield profitability of potato ( Solanum tuberosum L.) farmers. The present study was conducted to detect quantitative trait loci (QTL) controlling these traits. A tetraploid linkage map constructed using 808 single nucleotide polymorphisms (SNPs) from SolCAP ...

Virginia Agricultural Experiment Station; Small Grains Board; Maryland Grain Producers Utilization Kentucky Growers Association; U.S. Department of Agriculture through Wheat and Barley Scab Initiative [59-0206-9-084]; ARSUnited States (USDA)USDA Research Service [58-6645-0-0-108]; Hatch Program the National Institute Food (NIFA) [59-0790-4-102]; NIFA Triticeae Coordinated Project [201168002-300...

Neurons communicate with their target cells primarily by the release of chemical transmitters from presynaptic nerve terminals. The study of CNS presynaptic nerve terminals, isolated as synaptosomes (SSMs) has, however, been hampered by the typical small size of these structures that precludes the introduction of non-membrane permeable test substances such as peptides and drugs. We have develop...

Two ruminant acute phase proteins (APPs), haptoglobin (Hp) and serum amyloid A (SAA), were evaluated as serum biomarkers (BMs) for sheep scab-a highly contagious ectoparasitic disease caused by the mite Psoroptes ovis, which is a major welfare and production threat worldwide. The levels of both APPs increased in serum following experimental infestation of sheep with P. ovis, becoming statistica...

Oncolytic vaccinia virus (VACV) therapy is an alternative cancer treatment modality that mediates targeted tumor destruction through a tumor-selective replication and an induction of anti-tumor immunity. We developed a humanized tumor mouse model with subcutaneous human tumors to analyze the interactions of VACV with the developing tumors and human immune system. A successful systemic reconstit...

Virotherapy on the basis of oncolytic vaccinia virus (VACV) infection is a promising approach for cancer therapy. In this study we describe the establishment of a new preclinical model of feline mammary carcinoma (FMC) using a recently established cancer cell line, DT09/06. In addition, we evaluated a recombinant vaccinia virus strain, GLV-5b451, expressing the anti-vascular endothelial growth ...

Studies conducted during 2009-2013 at the Experimental Orchard located in the central region of Poland showed that the highest number of V. inaequalis pseudothecia occurred on ‘McIntosh’ and ‘Cortland’ leaves. A smaller number of pseudothecia was found on the leaves of the Alwa and Jonagold cultivars, but there were no statistical differences. The first discharges of ascospores were noted at a ...

Sheep scab is an intensively pruritic, exudative and allergic dermatitis of sheep caused by the ectoparasitic mite Psoroptes ovis. The purpose of the present study was to investigate the effect of P. ovis infestation on different components of the ovine epidermal barrier within the first 24 hours post-infestation (hpi). To achieve this, the expression of epidermal differentiation complex (EDC) ...