Dr Itch is evaluating a young man named Sam who has pruritic papules on his hands and genitals. A mineral oil preparation confirms scabies. Dr Itch recommends treatment with permethrin cream. Sam reveals that he lives with his girlfriend and brother, both of whom have developed symptoms suggestive of scabies. Neither Sam’s girlfriend nor his brother is a patient of Dr Itch. In fact, Sam confide...

Scabies, the human skin disease caused by infestation by the mite Sarcoptes scabiei var. hominis, causes considerable morbidity and mortality through direct effects and as a result of secondary bacterial infection. Scabies is a truly neglected disease, largely absent from the global health agenda, and its huge burden of disease is largely underappreciated. We contend that coordinated, global ef...

Scabies continues to be an important parasitic disease of humans, and other mammals. Suprisingly for a disease that has afflicted humans since antiquity, little is directly known about the basic biology of the parasite, the host-parasite interactions, the host immune response, and host susceptibility. Much more research in these areas is needed if we are to understand fully the occurrence, tran...

BACKGROUND Complications of scabies and impetigo such as glomerulonephritis and invasive bacterial infection in Australian Aboriginal children remain significant problems and the overall global burden of disease attributable to these skin infections remains high despite the availability of effective treatment. We hypothesised that one factor contributing to this high burden is that skin infecti...

Background The Solomon Islands is targeting elimination of malaria by 2030. The dominant vector is the predominantly exophagic, exophilic Anopheles farauti sensu strictu. This biting behaviour limits the efficacy of conventional vector control tools and highlights the need for new strategies. When administered to humans ivermectin has been shown to have a mosquitocidal effect. Mass drug adminis...

The aim of this study was to test the effect of Streptomyces scabies on the degradation of Gramonol herbicide in order to reduce its residual toxicity. Four isolates of S. scabies (St1, St2, St3, and St4) showed different ability to degrade the gramonol in vitro and in soil. They varied in their potential ability to degrade Gramonol in vitro after 5 days incubation, and after 35 days post herbi...

BACKGROUND Oral ivermectin is an alternative therapy for human scabies infection due to its ease of administration and good safety profile. However, there is no definitive consensus on the optimal dosing regimen. OBJECTIVE To describe the treatment of human scabies with different dosages of oral ivermectin and the possible adverse events. METHODS 23 patients with human scabies were treated ...

Scabies is a common parasitosis of the skin caused by Sarcoptes scabiei hominis. This infestation occurs in all geographic areas and across all age groups, races, and social classes. Poor economic conditions and lack of proper hygiene are risk factors for the disease. Subcorneal pustular dermatosis is characterized by numerous relapsing pustular eruptions on normal or mildly erythematous skin. ...