Case report An 83-year-old man with previous cerebral abscess (surgically resected 55 years prior) and postoperative seizure disorder presented with headache, scalp tenderness and reduced left eye visual acuity. His medications were: phenytoin 400mg daily, cilazapril 1.5mg daily, omeprazole 40mg daily, melatonin 3mg nightly, bendrofl uazide 2.5mg daily and primidone 500mg daily. Examination rev...

Merkel cell carcinoma (MCC) is a rare, aggressive skin tumor that mainly occurs in the elderly with a generally poor prognosis. Like all skin cancers, its incidence is rising. Despite the poor prognosis, a few reports of spontaneous regression have been published. We describe the case of a 89-year-old male patient who presented two MCC lesions of the scalp. Following biopsy the lesions underwen...

Erosive pustular dermatosis of the scalp is a rare inflammatory skin disease that mainly affects older patients and is characterized by the presence of sterile pustules and scabs. Recently, several authors have reported the usefulness of photodynamic therapy in the treatment of this condition. We present the case of a 79-year-old man with skin phototype III and actinic keratosis of the face and...

Actas Dermosifiliogr. 2007;98:372-6 373 To the Editor: We describe a 57-year-old man with multiple basal cell carcinomas on the scalp, where he had undergone radiation therapy in childhood. He consulted for a pearly mass adjacent to a violaceous mass of 5 cm that was poorly defined, indurated, asymptomatic, and with several peripheral nodules (Figure 1), but no local or regional lymph node enla...

In this article, we review some of the artifacts commonly observed in biopsies and the methods used to prevent their appearance. We describe the basic techniques for taking biopsies of melanocytic lesions, bullous diseases, and from special areas such as the scalp and nail region. We also provide a brief summary of the role of skin biopsy in the diagnosis of neurological diseases and prenatal d...

Amongstcommonest problems patients complain about when they visit their dermatologist is hair loss. Depression, distress and serious psychological disturbances are commonly related to it. Hair loss may last over both short and long time span. A great number of examinations have to be done in order to confirm the diagnosis, which includes laboratory testing, clinical tests, scalp biopsy and phys...

Cutaneous metastases from colorectal cancer are relatively uncommon presenting in fewer than 5% of patients but they are very important to recognize as they signify disseminated disease and poor prognosis. We describe a case a 62-year-old patient diagnosed with scalp metastasis during his systemic chemotherapy treatment for a colorectal carcinoma stage IVb who underwent excisional biopsy of the...

Alopecia areata (AA) is an autoimmune disease typified by nonscarring hair loss with a variable clinical course. In this study, we conducted whole genome gene expression analysis of 96 human scalp skin biopsy specimens from AA or normal control subjects. Based on gene expression profiling, samples formed distinct clusters based on the presence or absence of disease as well as disease phenotype ...

Methods Our patient is a 64 year-old female, who had glioma and had been on post-op anticonvulsants therapy. On the 3rd day after she had an operation, lansoprazole was added to the therapy. After the first lansoprazole dose erythematous dusky red macules were occured in extremities and trunk and on the following day confluent purpuric lesions tended to run together in 95% of the whole body inc...

We describe 8 children with hyper-IgE syndrome who had papulopustular eruption on the face and scalp in the first year of life. Seven of the 8 patients had persistent peripheral eosinophilia and 3 had leukocytosis noted before diagnosis. Skin biopsy specimens in 6 patients revealed spongiosis and perivascular dermatitis and/or folliculitis with a predominance of eosinophils. Two patients had bo...