Here, we describe a case of colonic sarcoidosis that developed over a 7-year period of observation of intrathoracic sarcoidosis. The patient was asymptomatic, but colonoscopy showed multiple elevated lesions mimicking submucosal tumors in several areas of the colon. The specimens obtained by biopsy showed noncaseating granuloma, suggesting sarcoidosis. The observations in the present case indic...

References CHAPMAN, J.S. (1955) Note on the secondary factors involved in the etiology of sarcoidosis. American Review of Tuberculosis, 71, 459. COLOVER, J. (1948) Sarcoidosis with involvement of the nervous system. Brain, 71, 451. DA COSTA, J.L. (1973) Geographic epidemiology of sarcoidosis in South East Asia. American Review of Respiratory Disease, 108, 1269. HSING, C.T. (1964) Sarcoidosis am...

Rationale: Management of sarcoidosis patients with the potential for multi-organ involvement can be complex and require the expertise of multiple specialties. Objectives: Our goal was to estimate the current number of clinics dedicated to the management of patients with sarcoidosis, and to evaluate what clinic structures and definitions currently exist. Methods: A link to an online survey was e...

BACKGROUND Cases of tattoo sarcoidosis reported in English and French literature have recently been reviewed; however, only two Japanese patients were included in the review because most Japanese patients were reported in Japanese journals. OBJECTIVES To determine the clinical characteristics of Japanese tattoo sarcoidosis. METHODS We reported a Japanese female with tattoo sarcoidosis, and ...

BACKGROUND In recent years we have observed with increasing frequency granulomatous papular lesions involving the knees, for which we proposed the term papular sarcoidosis of knees. OBJECTIVES To evaluate the clinicopathological features of papular sarcoidosis of the knees. METHODS Patients with papular lesions of the knees and histopathologically sarcoid granulomas were included in the stu...

OBJECTIVE Sarcoidosis is a systemic inflammatory disorder characterized by granulomas. Although the aetiology is unknown, sarcoidosis is thought to be mediated by Th1 lymphocytes. Recently, IL-17A has been implicated in granuloma formation in various diseases, including tuberculosis. Therefore, we hypothesized that Th17 cells play a role in sarcoidosis, paralleling recent findings in autoimmune...

INTRODUCTION Sarcoidosis is a multisystem disease characterized by the presence of non-caseating granulomas in affected organs. Almost 70% of patients with a sarcoidosis reaction have hepatic involvement. However, evidence-based clinical management or treatment strategies for hepatic sarcoidosis are poorly defined. Here, we present a case of a resected hepatic sarcoidosis patient. Additionally,...

Question: A 29-year-old man with a past medical history significant only for an open appendectomy appendicitis as child presented complaints of right-sided abdominal flank pain. Upon further interview, he endorsed colicky pain approximately 1 year intermittent nausea, vomiting, and weight loss 15–20 pounds. He admitted to passing flatus but had not bowel movement 3 days. Physical examination sh...

The facial nerve is commonly involved in neural sarcoidosis, but there is only one reported case in which bilateral facial paralysis was the sole manifestation of sarcoidosis. We report a case of sarcoidosis presenting with bilateral facial paralysis as the only sign. The pathology, clinical presentation, pathophysiology and diagnosis of sarcoidosis has been discussed.