The renal involvement is common in any form of systemic vasculitis. These include classic polyarteritis nodosa, Wegener’s granulomatosis, microscopic polyarteritis, Churg-Strauss syndrome, and the hypersensitivity vasculitides (including Henoch-Schönlein purpura, mixed cryoglobulinemia, and serum sickness). Also vascultitis secondary to rheumatological disorders such as rheumatoid arthritis can...

background: henoch-schönlein purpura (hsp) is an lga mediated small vessel systemic vasculitis disease in children. the etiology and pathogenesis of hsp disease remain unknown. however, environmental and genetic risk factors could play important roles in susceptibility to hsp disease. in this study we investigated the association of 5՛-untranslated region polymorphism (-634g/c) of vegf gene wit...

Serum levels of C1q, C4, C3, C5, factor B, and properdin were measured in patients with Henoch-Schönlein purpura (HSP). In the cases of acute HSP, 9 of 23 (39%) had a low CH50, and 5 of 17 (30%) a low properdin; C1q, C4, and C3 levels were not depressed. In 10 cases with chronic nephritis following HSP, complement components were normal except for 2 with reduced C4 and one with low properdin. T...

Received April 5, 2012, Revised May 25, 2012, Accepted for publication June 3, 2012 Corresponding author: Mutlu Cayirli, Department of Dermatology, Agri Military Hospital, Merkez, 04200, Agri, Turkey. Tel: 90-537-62076-79, Fax: 90-472-216-27-47, E-mail: [email protected] This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http...

To further investigate into the relapses of Henoch-Schönlein purpura (HSP), we analyzed the frequency, clinical features, and predictors of relapses in series of 417 unselected patients from a single center. After a median follow-up of 12 (interquartile range [IQR]: 2-38) years, almost one-third of the 417 patients (n = 133; 32%; 85 men/48 women) had experienced at least 1 relapse. At the time ...

A review of 76 Southampton children with Henoch-Schönlein purpura has confirmed that there is no evidence of a streptococcal aetiology in the majority of cases of this disease. Among these patients the frequency of preceding respiratory infection of all kinds was only 7 percent greater than that in controls. Data on month of admission in four areas of England and Scotland show that the incidenc...

Dear Editor, Mononeuritis multiplex (MM) is a syndrome of the peripheral nervous system (PNS) involving progressive multifocal peripheral nerve lesions. Its distribution is typically asymmetric, and the course of the disease varies with the underlying etiology. MM is associated with several medical conditions, including vasculitis, immune-mediated diseases, diabetes, infections, neoplasms, infi...