BACKGROUND The effect of specific immunotherapy (SIT) on eczema in atopic dermatitis is not known. Therefore, a multi-centre, randomized dose-response trial, double-blind with respect to the efficacy of a biologically standardized depot house dust mite preparation was performed. METHODS Eighty-nine adults with a chronic course of atopic dermatitis, SCORAD >or=40 and allergic sensitization to ...

5mg/D), and a short course of oral corticosteroids (prednisone 1mg/kg/D) We recorded mild clinical improvement of dermatitis at first month of therapy (SCORAD 71.9) After three months, our patient showed spectacular improvement of symptoms score and quality of life (SCORAD 30.2). Now, he continues with monthly immunotherapy with excellent tolerance. He practices judo without affectation of the ...

In this study we investigated skin bacterial colonization, allergen-specific IgE and antiphospholipid/antinuclear antibodies in 72 children with atopic eczema/dermatitis syndrome (age 2-17 years). Bacteria were found on the skin in 41 cases and serological allergen-specific IgE positivity in 37. The different forms of antibodies appeared in the ratio 21/72 (33 antibodies in 21 children). The oc...

In this study we investigated skin bacterial colonization, allergen-specific IgE and antiphospholipid/antinuclear antibodies in 72 children with atopic eczema/dermatitis syndrome (age 2 – 17 years). Bacteria were found on the skin in 41 cases and serological allergen-specific IgE positivity in 37. The different forms of antibodies appeared in the ratio 21/72 (33 antibodies in 21 children). The ...

Atopic dermatitis is one of the most prevalent chronic inflammatory skin diseases, which can vastly influence patients quality life. Objective assessment severity required to select adequate therapy and evaluate its effectiveness. Heterogeneous clinical manifestations with greatly varying make it difficult assess atopic dermatitis. More than twenty methods are developed for this diseases severi...

The new scoring system for assessment of the extent and severity of skin inflammation index in atopic dermatitis patients, W-AZS, is presented. The system provides detailed assessment of both subjective and objective signs and symptoms of atopic dermatitis. With the use of W-AZS, acute and chronic skin manifestations of inflammatory process are appropriately evaluated and scored. It also enable...

BACKGROUND The present increased incidence of atopic diseases has been associated with an altered intake of essential fatty acids (EFAs). The composition of blackcurrant seed oil (BCSO) corresponds to the recommended dietary intake of EFAs, and as a dietary supplement could, in small doses, modify the imbalance of EFAs in an efficient way. OBJECTIVE To assess the effect of dietary supplementa...

Irritation of the skin of patients with atopic dermatitis by contact with rough fibres of synthetic or woollen clothes is well known. Therefore, it has been recommended that patients should wear cotton clothes. However, cotton also consists of rough fibres able to irritate the skin, whereas silk is characterized by smooth fibres without irritating potential. The aim of our study was to evaluate...

Atopic dermatitis (AD) is a chronic cutaneous inflammatory disease. Various categories of therapeutic medications are used for treating AD. Omalizumab is a monoclonal anti-IgE antibody that binds to IgE molecules at the high-affinity receptor (FcepsilonRI) binding site. Therefore, omalizumab can be used as a potential new systemic treatment agent for recalcitrant AD patients with elevated IgE l...

BACKGROUND AND OBJECTIVE The aim of this study was an evaluation of the dependence between the severity of atopic dermatitis evaluated with the Scoring Atopic Dermatitis (SCORAD) index and the occurrence of other atopic diseases and parameters. METHODS The complete dermatological and allergological examinations were performed. The statistical evaluation of the dependence between the occurrenc...