My argument is that SPMS, characterised by steadily progressive, predictive disability, cerebral and spinal cord atrophy and neuroaxonal death is, purely and completely, a secondary effect of the preceding and ongoing inflammatory disease process. The disappearance of hand surgeons in rheumatology The management of rheumatoid arthritis, the corresponding disorder in rheumatology, has been revol...

An approach for predicting incident durations that are susceptible to severe congestion, the occurrence of secondary incidents, and their joint effect is proposed. First, a fuzzy entropy feature selection methodology is applied to determine redundant factors and rank factor importance with respect to their contribution on the predictability of incident duration. Second, neural network models fo...

let ‎x be an ‎‎n-‎‎‎‎‎‎square complex matrix with the ‎cartesian decomposition ‎‎x = a + i ‎b‎‎‎‎‎, ‎where ‎‎a ‎and ‎‎b ‎are ‎‎‎n ‎‎times n‎ ‎hermitian ‎matrices. ‎it ‎is ‎known ‎that ‎‎$vert x vert_p^2 ‎leq 2(vert a vert_p^2 + vert b vert_p^2)‎‎‎$, ‎where ‎‎$‎p ‎‎geq 2‎$‎ ‎and ‎‎$‎‎vert . vert_p$ ‎is ‎the ‎schatten ‎‎‎‎p-norm.‎ ‎‎ ‎‎in this paper‎, this inequality and some of its improvements ...

objectives: joint attention is one of the most important prerequisite of language and social development. there are two types of joint attention, initiating joint attention and responding to joint attention. this study examined the development of responding to joint attention in typically developing children in 8-30 month. methods: this study was cross-sectional. 61 children (40 female and 20 m...

In many case-control genetic association studies, a secondary phenotype that may have common genetic factors with disease status can be identified. When information on the secondary phenotype is available only for the case group due to cost and different data sources, a fitting linear regression model ignoring supplementary phenotype data may provide limited knowledge regarding genetic associat...

In this report we present our experiences with knee arthrodesis nails as a secondary salvage procedure after severe knee injuries at a level-one trauma centre. Exemplary two cases of subtotal amputation are discussed. Both cases, of totally destroyed knee joints, were treated with a unilateral external fixator, shortening and secondary bifocal distraction osteogenesis. In one case nailing after...

OBJECTIVES Radiofrequency facet joint denervation procedures have been common practice for 2 decades in treatment of chronic low back pain. We designed this multicenter, randomized, double-blind, sham treatment controlled trial to determine the efficacy of radiofrequency facet joint denervation, as it is routinely performed. METHODS Inclusion criteria were low back pain, duration more than 6 ...

The meniscus has several important roles, such as transmission of the load, absorption of the shock in the knee joint, acting as a secondary anteroposterior stabilizer of the knee joint, and contributing to proprioception of the knee joint. Degenerative changes of the knee joint develop in the long-term follow-up even after partial meniscectomy. Thus, there has been growing interest in meniscal...

It is being gradually accepted that osteoarthrosis should be regarded in functional terms and, for investigative purposes, as 'joint failure'. Various anatomical, metabolic, and tissue factors can all produce the same end result in the final common pathway of cartilage degeneration, pain, and loss of joint function. Thus osteoarthrosis is a heterogeneous disease that is age-related but is not m...

Arthrogryposis has been the term used to describe multiple congenital contractures for over a century. It is a descriptive term and present in over 400 specific conditions. Responsible gene abnormalities have been found for more than 150 specific types of arthrogryposis. Decreased fetal movement is present in all affected individuals which leads to a variety of secondary deformations. Decreased...