Steve Hickey, Hilary Roberts The Cochrane review by Douglas et al. [1], which is referenced in the Best Practice article by Douglas and Hemilä [2], covers 60 years of research into vitamin C and the common cold. However, the review omits pharmacokinetic data that invalidate the conclusion that vitamin C is ineffective. This conclusion is not derivable from the data presented. The dual-phase pha...

Secondary metabolites are organic molecules that are not involved in the normal growth and development of an organism. While primary metabolites have a key role in survive of the species, playing an active function in the photosynthesis and respiration, absence of secondary metabolites does not result in immediate death, but rather in long-term impairment of the organism’s survivability, often ...

To estimate the incidence and causes of secondary thrombocytosis in children, a 12 month study of all patients attending a children's hospital and discovered to have a platelet count over two times the upper normal limit (> 800 x 10(9)/l) was undertaken. Data so obtained were analysed both separately and together with those from two previous studies to gain as broad a perspective as possible. O...

background:: this study aimed to quantify the prevalence of low back pain (lbp), analyze its associated risk factors and explore on how lbp affects job satisfaction among 120 school teachers in malaysia. method: a cross-sectional study was conducted among randomly selected teachers from four secondary schools in putrajaya from february to march 2015. the level of lbp was assessed using a standa...

background: the phylogenetic location of chinese spirometra sparganum isolates remains unclear. the aim of this study was to explore the phylogenetic location of the spirometra sparganum isolates from china. methods: the 28s ribosomal dna (rdna) d1 sequences of 14 spirometra sparganum isolates collected from thirteen locations in china were analyzed by using neighbor-joining (nj), maximum parsi...

background: rna molecules play many important regulatory, catalytic and structuralroles in the cell, and rna secondary structure prediction with pseudoknots is one themost important problems in biology. an rna pseudoknot is an element of the rna secondary structure in which bases of a single-stranded loop pair with complementary basesoutside the loop. modeling these nested structures (pseudokno...

conclusions corticosteroid pulse therapy in spms was effective in inflammatory process, but could not postpone or decline the neurodegenerative process and besides the imposing side effects could not result in significant improvement in edss and mri plaques number in long term. patients and methods a double blind randomized controlled clinical trial was performed on 71 patients with spms referr...

in 1909, several years before the famous `organizer’ experiments of spemann and mangold, ethel browne demonstrated induction of a secondary axis in hydra by grafting a hypostome. based on this and subsequent work, in the late sixties, lewis wolpert proposed the theory of morphogen gradients and positional information. we have studied secondary axis induction by hypostome and foot tissue using t...

background: the aim of this study was to evaluate the reduction in excision cavity volume (ecv) during the whole breast radiotherapy (wbrt). the delineating of reduced cavity volume on secondary ct (computed tomography) might decrease the field size of boost plan. materials and methods: twenty patients were treated having breast conservative surgery. at first, primary ct simulation (ct-1) was d...