Brucellosis is a zoonotic disease in human and animals. Brucella melitensis is one of the most pathogenic species of Brucella in goat and sheep. Omp31 is an outer membrane protein of Brucella that acts as an immunogenic protein. Cytokines are glycoproteins with low molecular weight that play the role of an immune adjuvant and regulate immune responses. Interleukin-2 is one of the most important...

YopN is a secreted protein that prior to secretion directly interacts with the cytosolic SycN/YscB chaperone complex and TyeA. This study identifies a secreted YopN-TyeA hybrid protein that is expressed by Yersinia pestis, but not by Yersinia enterocolitica. DNA sequence analysis and site-directed mutagenesis studies demonstrate that the hybrid protein is the result of a +1 translational frames...

the clara cell protein (cc16) is a small and readily diffusible protein of 16 kda secreted by bronchiolar clara cells in the distal airspaces. mutation detection methods identified an adenine to guanine substitution in the cc16 gene at position 38 (a38g) downstream from the transcription initiation site within the non-coding region of exon 1. in the present study, the genetic polymorphism of cc...