background: closure of patent ductus arteriosus (pda), ventricular septal defect (vsd) and atrial septal defect (asd) can be done surgically or by device. this study was designed to compare the total cost of surgical or device closures of pda, asd or vsd for iranian patients. methods: this is a cross-sectional study, conducted from january 1, 2005 until january 1, 2006 in two large heart center...

Background: Atrial septal defect is a common congenital heart anomaly results in hemodynamically significant right ventriclular volume overload and an increase the pulmonary venous flow.
 Aim: Evaluate changes of flow parameters after transcatheter closure secundum atrial defect.
 Patients Methods: 50 patients with aged from 3.5 to 31 years were included study. Pulmonary Doppler ventr...

BACKGROUND Atrial septal defect often become more severe when encountered in genetic syndromes. Congenital disorder of glycosylation type 1a is an inherited metabolic disorder associated with mutations in PMM2 gene and can affect almost all organs. Cardiac abnormalities vary greatly in congenital disorder of glycosylation type 1a and congenital heart defects have already been reported, but ther...

Isolated atrial septal defects (ASD) represent 7% of all cardiac anomalies and can present at any age. Adolescents and adults with simple congenital heart disease such as isolated atrial septal defects are more likely to reach adult age without being diagnosed. Secundum ASD (sASD) is by far the most common type, occurring in 1/1500 live births, with 65% to 75% involving females. On the other ha...

Background—Volume overload of the pulmonary circulation in patients with atrial septal defect (ASD)-type secundum causes pulmonary vascular disease over a long period of time. This study aimed at (1) evaluating pulmonary vascular resistance (PVR) and (2) investigating the relation between PVR and exercise capacity in patients with open and closed ASD. Methods and Results—Forty-six patients with...

We report the management of a patient with secundum atrial septal defect (ASD) and severe pulmonary hypertension. A 65-year-old male with recently diagnosed atrial septal defect was referred to our centre for decompensated right heart failure with rest and exercise induced dispnea and severe pulmonary hypertension. Right heart catheterization confirmed a mean pulmonary pressure of about 55 mmHg...

Sinus node dysfunction in patients after repair of the secundum atrial septal defect has been ascribed to surgical damage. We studied 15 consecutive patients with secundum atrial septal defect before operative intervention. Noninvasive testing included 34-hour electrocardiographic monitoring and a standard 13-lead ECG. Intracardiac electrophysiologic techniques included corrected sinus node rec...

During the past several years therapeutic catheterization techniques have been developed to provide nonsurgical treatment for children with congenital aortic valve stenosis,',2 subvalvar aortic sten o ~ i s , ~ mitral s ten~s is ,~ ,~ and coarctation of the a ~ r t a . ~ , ~ Transcatheter therapy is now generally regarded as the treatment of choice for children with valvar pulmonic stenosis, pu...

OBJECTIVE Transcatheter closure of secundum atrial septal defect (ASD) with Amplatzer device is an alternative procedure to surgical repair, with some limitations. The aim of this study was to assess the initial and mid-term results of the treatment of ASD with Amplatzer septal occluder in children and adolescents. METHODS From May 2003 to January 2008 sixty three consecutive children and ado...

Conduction time from the region of the sinus node to the region of the atrioventricular (A-V) node was studied during open heart surgery in 13 patients with an endocardial cushion type atrial septal defect, eight patients with a secundum type atrial septal defect, one patient with a sinus venosus type atrial septal defect, and eight patients with an intact atrial septum. Internodal conduction t...