Despite an increased interest in the use of hydrogel encapsulation and cellular self-assembly (often termed "self-aggregating" or "scaffold-free" approaches) for tissue-engineering applications, to the best of our knowledge, no study to date has been undertaken to directly compare both approaches for generating functional cartilaginous grafts. The objective of this study was to directly compare...

BACKGROUND Prognostic models including age, self-rated health and prior sickness absence (SA) have been found to predict high (≥ 30) SA days and high (≥ 3) SA episodes during 1-year follow-up. More predictors of high SA are needed to improve these SA prognostic models. The purpose of this study was to investigate fatigue as new predictor in SA prognostic models by using risk reclassification me...

Norepinephrine (NE) secretion within the hypothalamic paraventricular nucleus (PVN) is pivotal to endocrine and behavioral responses. Activation of NE afferents to PVN also is necessary for the hypothalamo-pituitary-adrenal axis response to passively administered nicotine. The mode of drug delivery is a critical determinant of the dynamics of neurotransmitter secretion, yet the PVN NE response ...

introduction: teaching medical professionalism is increasingly acknowledged as an important aspect of medical education. the professionalism mini-evaluation exercise (p-mex) is an assessment tool for evaluating medical professionalism, but no studies using it as a self-assessment instrument have been reported. this paper reports on a preliminary investigation of the finnish version of the p-mex...

OBJECTIVE This study presents evaluative data on the Childhood Experiences of Violence Questionnaire (CEVQ), a brief, self-report measure of youth victimization. METHODS Literature reviews, expert consultations and qualitative interviews informed the development of the CEVQ. Test-retest reliability of the preliminary and final versions of the CEVQ was examined. Child welfare workers (n=11) as...

OBJECTIVE In subjects at high risk for sleep apnea (SA), aldosterone concentrations correlate with severity of SA and primary aldosteronism (PA) is very often diagnosed. Patients with PA show a high prevalence of SA. Treatment of PA either by adrenalectomy (ADX) or mineralocorticoid receptor (MR) blockade is thought to abolish the increased comorbidities. However, no data are available regardin...

Salicylic acid (SA), which is central to defense mechanisms in plants and the principal metabolite of aspirin, occurs naturally in man with higher levels of SA and its urinary metabolite salicyluric acid (SU) in vegetarians overlapping with levels in patients on low-dose aspirin regimens. SA is widely distributed in animal blood. Fasting for major colorectal surgery did not cause disappearance ...

Dr. Ullman is from the University of Alabama at Birmingham. Drs. DiCarlo and Ferringer are from Geisinger Medical Center, Danville, Pennsylvania. The authors report no conflict of interest. Correspondence: David Ullman, MD ([email protected]). H&E, original magnification ×20 (inset, original magnification ×200). Eligible for 1 MOC SA Credit From the ABD This Dermatopathology Diagnosis article ...

In view of increasing application of sensitivity assessment (SA) to environmental simulation models, a relatively short, informal introduction to aims and methods of SA is given. Their variety, motivation and scope are illustrated byoutlines of a broad selection of approaches.Methods based on derivatives, algebraic analysis, sparse sampling, variance decomposition, Fourier analysis and binary c...

RATIONALE, AIMS AND OBJECTIVES Loss of situation awareness (SA) by health professionals during handover is a major threat to patient safety in perinatal care. SA refers to knowing what is going on around. Adequate handover communication and process may support situation assessment, a precursor of SA. This study describes current practices and opinions of perinatal handover to identify potential...