To cite: Grandhi R, Williamson RW, Zwagerman NT, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2015212019 DESCRIPTION A 34-year-old man with a history of seizures presented after a generalised seizure. An MRI of the brain and MR angiogram of the brain (figure 1) were performed, demonstrating a partially thrombosed, giant intracranial aneurysm involving th...

This paper describes the design and analysis of a particular micro-electromechanical-system (MEMS) micromirror device that can be used for an optical switching application. Analytical expressions for electrostatic torque and restoring torque of serpentine springs are derived. The performance of the proposed structure is compared with the existing structures having straight torsional beams. The ...

Snakes are a remarkably diverse and successful group today, but their evolutionary origins are obscure. The discovery of snakes with two legs has shed light on the transition from lizards to snakes, but no snake has been described with four limbs, and the ecology of early snakes is poorly known. We describe a four-limbed snake from the Early Cretaceous (Aptian) Crato Formation of Brazil. The sn...

Analytical models to describe coupling between different directions of motion are derived using energy methods and verified for the U-spring, crab-leg spring and the serpentine spring. Finite element analyses (FEA) are done for a range of spring dimensions for each spring type in order to verify the models and determine the validity range. The models for the serpentine spring are then incorpora...

This article presents a historical review of mathematics education since the late 1950s in the United States. Three themes are used to organize the literature reviewed in the article: (a) broad sociopolitical forces, particularly highly publicized educational policy statements; (b) trends in mathematics research; and (c) theories of learning and instruction. At times, these themes coincide, as ...

We analyzed botanical, geologic, and climatic data in an effort to understand why there are many more serpentine endemics—i.e., plant species restricted to ultramafic substrates—in some regions of California than in others. We found that, in addition to elevational range (which subsumed the effect of serpentine area) and annual rainfall, the age of exposure of serpentine explained significant g...

the mesolimbic dopamine (da) system contains both d1-like and d2-like receptors, has been connected to control of locomotor behavior. an apparent role for d1 and d2 receptors throughout the mesolimbic system in the alteration of locomotor behavior has been demonstrated in pharmacological studies. the nucleus accumbens (nac) is comprised of a core and a shell subregion, which is a component of t...

Interactions between microtubules and filamentous actin (F-actin) are crucial for many cellular processes, including cell locomotion and cytokinesis, but are poorly understood. To define the basic principles governing microtubule/F-actin interactions, we used dual-wavelength digital fluorescence and fluorescent speckle microscopy to analyze microtubules and F-actin labeled with spectrally disti...

Compositional variations of talc in peridotites and serpentinites could have significant implications for modeling geochemical cycles involving the upper mantle but been scarcely studied. We analyzed chemical compositions prograde retrograde associated minerals thermally metamorphosed from Southwest Japan. The has Si, Al, Mg, Fe, Na contents. Most Fe indicate mechanical mixing with serpentine c...

Leukocyte functions are linked to their migratory responses, which, in turn, are largely determined by the expression profile of classical chemokine receptors. Upon binding their cognate chemokines, these G-protein-coupled receptors (GPCRs) initiate signaling cascades and downstream molecular and cellular responses, including integrin activation and cell locomotion. Chemokines also bind to an a...