I F NO INTRAVASCULAR liberation of intracellular hemoglobin occurs with the transfusion of thawed, recOllstituted frozen erythrocytes, the amount of free supernatant hemoglobin in units of frozen blood that may be infused without producing henioglobinuria is determined principally by the recipient’s plasma llenloglobin-billdillg capacity (1, 2). Oweii et al. (3) reported a method for quantitati...

We studied serum proteomic profiling in patients with graft versus host disease (GVHD) after allogeneic hematopoietic cell transplantation (allo-HCT) by two-dimensional gel electrophoresis (2-DE) and mass spectrometry analysis. The expression of a group of proteins, haptoglobin (Hp), alpha-1-antitrypsin, apolipoprotein A-IV, serum paraoxonase and Zn-alpha-glycoprotein were increased and the pro...

Forty-three women who had viral hepatitis one or more years ago and 35 healthy women who were age and parity matched were given an oral contraceptive containing 0.05mg ethinyl estradiol and 0.5mg levonorgestrel for six consecutive months. Liver function tests (serum bilirubin, SGOT, SGPT and serum alkaline phosphatase) and serum proteins (total, albumin, globulins, ceruloplasmin, haptoglobin an...

OBJECTIVE The haptoglobin 2-2 genotype is associated with lower haptoglobin concentrations and atherosclerosis in diabetes. Endothelial cell apoptosis contributes significantly to atherosclerosis. We studied endothelial cell apoptosis in diabetes patients with haptoglobin 2-2 and non-haptoglobin 2-2 genotype. Approach and results: We pooled plasma from 10 patients with haptoglobin 2-2 and non-h...

the effect of serum proteins or indomethacin on prostaglandin synthase is assayed important in determining the potency of inhibitors, but also the fact that studies of inhibition of a complex multienzyme system such as ‘prostaglandin synthase’, even under optimal conditions, are complicated by the fact that haptoglobin and albumin can interact with different components of the enzyme ststem (Den...