Medicinal plants have been widely employed in treating various diseases for centuries and are still a major resource and repository that can be further exploited for a variety of infectious and non-infectious ailments. The popularity of medicinal herbs has grown significantly in recent years despite a dearth of information regarding their modes of action and continuing concerns over their effic...

Parthenium hysterophorus known as congress grass belongs to the family compositae. Direct contact with plant and plant parts, living or dead, result in dermatitis in mankind. Presence of pollen in air causes diseases, like fever and asthma (Kaur and Sharma, 1986; Lonkar et al., 1974; Rodriguez, 1975; Rodriguez et al., 1976a and b; Shen et al., 1976; Subba Rao et al., 1976, 1978). Live stocks ar...

In this study, we present a proposal for the physical and chemical quality control of the powder of the species T. parthenium (feverfew) and its hydroalcoholic extract obtained by percolation. The sesquiterpene lactone parthenolide, the main active compound of this plant, was quantifi ed by HPLC and its content was found to be 0.49% in the powder and 1.06% in the extract. The total content of f...

A novel agarofuran sesquiterpene polyol ester, 1beta,2beta,6alpha,15beta-tetracetoxy-8 beta,9alpha-dibenzoyloxy-beta- dihydroagarofuran (celahin D) (1), two known analogues of 1,1beta-acetoxy-8beta,9alpha-dibenzoyloxy-4al pha6alpha-dihydroxy-2beta(alphamethylbutanoyloxy)-beta-++ +dihydroagarofuran (2) and beta-acetoxy-8beta,9alpha-dibenzoyloxy-6alpha-hy droxy-2beta(alpha -methylbutanoyloxy)-bet...

An unusual dimeric guaianolide, artemilinin A (1) and a sesquiterpene-monoterpene lactone, isoartemisolide (2), were isolated from the leaves of Artemisia argyi. Their structures were elucidated on the basis of extensive spectroscopic analysis (IR, HR-ESIMS, 1D- and 2D-NMR), and the absolute configurations were determined by CD spectra and quantum chemical ECD calculation. Furthermore, in in vi...

Feverfew (Tanacetum parthenium) is a medicinal herb that has long enjoyed traditional use as a remedy for migraine headache pain. The aerial parts of Feverfew (flowers, leaves and stems) contain parthenolide (a sesquiterpene lactone) which is believed to be responsible for the plant's biological activity. Dried feverfew aerial parts should contain approximately 0.2-0.5 wt.% parthenolide and adu...