OBJECTIVE To determine whether the use of additional preoperative imaging was cost-effective compared with bilateral neck exploration (BNE) for the treatment of primary hyperparathyroidism in patients with negative findings on scans with technetium Tc 99m sestamibi. DESIGN We performed a cost-effectiveness analysis. The decision whether to proceed to BNE or obtain additional preoperative imag...

UNLABELLED The purpose of this study was to develop an in vivo imaging protocol for a high-resolution stationary SPECT system, called FASTSPECT, in a rat heart model of ischemia-reperfusion (IR) and to compare 99mTc-sestamibi imaging and triphenyltetrazolium chloride (TTC) staining for reliability and accuracy in the measurement of myocardial infarcts. METHODS FASTSPECT consists of 24 modular...

OBJECTIVE To investigate why some patients with single parathyroid adenomas have negative preoperative sestamibi scans. DESIGN Retrospective review. SETTING Tertiary care center. PATIENTS Twenty-one patients with false-negative (FN) scans were compared with 22 patients with true-positive (TP) scans. All patients had single parathyroid adenomas. INTERVENTIONS Neck exploration and removal...

We sought to summarize the published evidence regarding the measurement of infarct size by serum markers, technetium-99m sestamibi single-photon emission computed tomography (SPECT) myocardial perfusion imaging, and magnetic resonance imaging. The measurement of infarct size is an attractive surrogate end point for the early assessment of new therapies for acute myocardial infarction. For each ...

OBJECTIVES Although transgenic mice have emerged as powerful experimental models of cardiovascular disease, methods for in vivo phenotypic assessment and characterization remain limited, motivating the development of new instruments for biologic measurement. BACKGROUND We have developed a single-photon emission computed tomography system with a pinhole collimator (pinhole SPECT) for high-reso...

Com intuito de detectar a predição da resposta ao tratamento quimioterápico em carcinoma mama triplo negativo (CMTN), assim como, um padrão específico, propusemos cintilografia mamas com sestamibi-99mTc como método diagnóstico para avaliação. Foram estudadas 49 pacientes, no período 2011 2016, CMTN submetidas à pré-quimioterapia neoadjuvante e avaliação do espécime cirúrgico. Na foram avaliadas...

we present a female patient with atypical chest pain who was referred to our department for ischemia evaluation. 99mtc-mibi myocardial perfusion scan with dipyridamole stress was performed. sub-diaphragmatic activity in the hepatic tissue and then in the bowel loops caused severe overlap on the inferior wall even on consecutive delayed images. dipyridamole stress was repeated for the patient wi...

aim: thyroid scan with sestamibi is used for evaluation of thyroid nodules with the aim of increasing specificity before surgery. in this study we evaluated the role of sestamibi thyroid scan in candidates for thyroid surgery. methods and patients: during two years, 37 patients were studied with solitary thyroid nodules, referred for thyroid surgery due to malignant or suspicious fnab results (...

Outcome: Twenty-three women and 14 men were followed after RGS for 35.4 + 12.5 months (range 9-57). There were 33 papillary (one “tall” cell variant), 2 follicular, and 2 Hürthle cell cancers. In 7 patients, thyroid cancer recurred in the neck while cervical lymph node metastases were found in 31 patients (one patient had papillary cancer both in the thyroid bed and cervical lymph nodes). Sixty...