نتایج جستجو برای: severe combined immunodeficiency
تعداد نتایج: 782574 فیلتر نتایج به سال:
scid is a lethal genetic autosomal recessive disorder that has been observed in humans, dogs, mice, and horses. affected animals are incapable of generating specific antigens for immune responses needed to protect them from infectious diseases. the frequency of affected recessive allele varies in different regions so that the outcome of normal breeding with carriers of recessive alleles is diff...
INTRODUCTION If left untreated, severe combined immunodeficiency can lead to an acute susceptibility to infection. The intrauterine environment is sterile until the amniotic membranes rupture. The vaginal flora then ascends into the genital tract, thus increasing the risk of chorioamnionitis. An extremely premature and prolonged membrane rupture is associated with a dismal prognosis for an immu...
We describe procedures for determining cytosine and orotic acid in urine. We determine cytosine by cation-exchange analysis with either HCl or pH 5.2 buffer as eluent. Orotic acid is first separated by an anion-exchange separative procedure; after lyophilization, the product is subjected to "high-pressure" liquid chromatography for further separation and detection. We analyzed urine from normal...
Adverse reactions induced by BCG vaccination are rare and appear either in the form of lymphadenitis or osteitis. One of the rarest complications of the vaccine is disseminated mycobacterial infection which mostly occurs in infants with immune deficiency. In this paper a case of disseminated BCG infection is reported in a four-month-old infant suffering from severe combined immunodeficiency (SC...
BACKGROUND Treatment of rare severe side effects of vaccinia virus (VACV) immunization in humans is currently very challenging. VACV possesses two immunologically distinct virion forms in vivo - intracellular mature virion (MV, IMV) and extracellular virion (EV, EEV). METHODS Antibody-mediated therapeutic efficacy was determined against VACV infection in a small animal model of progressive va...
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