OBJECTIVE This study compares treatment with a polihexanide-containing biocellulose wound dressing (BWD+PHMB) versus the best local standard of silver dressings (Ag) in painful, critically colonised (wounds-at-risk) or locally-infected wounds. METHOD Patients with wounds of various aetiologies, a baseline VAS pain score >4 and a semi-quantitative bacterial load of ++ or higher were randomly a...

Bacterial contamination on external wounds is known to be a factor that prevents wound healing and triggers tissue damage. Hydrogel-dressings with antibacterial activity useful medical device avoid this contamination, wherein the can provided via incorporation of silver nanoparticles (AgNPs). Contrary conventional two-step preparation an AgNPs-loaded hydrogel ([email protected]), work aims esta...

Wound infection is considered a significant challenge in skin injuries. Sprayable antibacterial wound dressings are interesting alternatives to their traditional counterparts because of facile preparation, ease-of-use, and the possibility topical delivery materials. Herein, novel sprayable formulated reported. The were developed by in-situ formation Ag-nanoparticles (Ag-NPs) using Persian gum (...

Skin wound healing is time-consuming and frequently accompanied by bacterial infections the development of scars. The rise antibiotic-resistant strains has sparked a growing interest in naturally occurring bioactive substances, like curcumin, that possess wound-healing capabilities. Silver natural antimicrobial agent, finds extensive use specialized dressings. nanoparticles (AgNPs) were synthes...

In recent years natural polymers have been widely used in biomedical applications. Application of natural and biocompatible polymers in wound dressing, medical sutures and tissue engineering are extensively growing. Additional properties are provided when metal nanoparticles such as silver and gold are incorporated in to the fibers. However, nowadays nanofibers due to their inherent properties ...

Polyvinyl alcohol (PVA) hydrogels are materials for potential use in burn healing. Silver nanoparticles can be synthesized within PVA hydrogels giving antimicrobial hydrogels. Hydrogels have to be swollen prior to their application, and the common medium available for that in hospitals is saline solution, but the hydrogel could also take up some of the wound's fluid. This work developed gamma-i...

PURPOSE: To analyze the healing effects of stromal vascular fraction (SVF) application compared to wound dressing with 2% silver sulfadiazine in full thickness burn wounds in rats. METHODS: Animals were divided into two groups: 2% silver sulfadiazine group and SVF group. Both groups received occlusive bandages while the first one was treated with 2% silver sulfadiazine and the latter was tr...

It was aimed to comparatively evaluate the effects of dressing methods with silver sulfadiazine, povidone-iodine, and saline which have a common use in routine practices for burn injuries. Twenty-eight Sprague Dawley adult female rats were used in this study. All the rats were divided into 4 groups: the control group, the povidone-iodine group, the saline group, and the silver sulfadiazine grou...

Sir, We read the article by Chopra on the increasing use of silverbased products with interest and we would like to make some observations. The title of the article asked whether there was cause for concern, and, understandably, the issue of resistance was raised in this respect. Chopra makes a case for using dressings that release high concentrations of silver in order to overcome this, yet, i...

Among the most difficult bacterial infections encountered in treating patients are wound infections, which may occur in burn victims, patients with traumatic wounds, necrotic lesions in people with diabetes, and patients with surgical wounds. Within a wound, infecting bacteria frequently develop biofilms. Many current wound dressings are impregnated with antimicrobial agents, such as silver or ...