Array manufacturers originally designed single nucleotide polymorphism (SNP) arrays to genotype human DNA at thousands of SNPs across the genome simultaneously. In the decade since their initial development, the platform's applications have expanded to include the detection and characterization of copy number variation--whether somatic, inherited, or de novo--as well as loss-of-heterozygosity i...

Fast, high efficiency and low error single-photon sources are required for the implementation of a number of quantum information processing applications. The fastest triggered single-photon sources to date have been demonstrated using epitaxially grown semiconductor quantum dots (QDs), which can be conveniently integrated with optical microcavities. Recent advances in QD technology, including d...

Efficient and bright single photon sources at room temperature are critical components for quantum information systems such as quantum key distribution, quantum state teleportation, and quantum computation. However, the intrinsic radiative lifetime of quantum emitters is typically ∼10 ns, which severely limits the maximum single photon emission rate and thus entanglement rates. Here, we demonst...

We have experimentally demonstrated the broadband enhancement of single-photon emission from nanodiamond NV centers coupled to planar multilayer metamaterial with hyperbolic dispersion. A tapered metamaterial waveguide for efficient outcoupling of high-k metamaterial modes has been numerically studied and fabricated. Introduction: The major thrust of research in quantum photonics is to build qu...

We present the case of an infant with medulloblastoma with extensive nodularity, which had been called cerebellar neuroblastoma. MR imaging clearly revealed a nodular enhancement, which appeared as a grape-like lesion. Single photon emission CT revealed markedly high iodine-123 metaiodobenzylguanidine uptake in the enhancing tumor. Iodine-123 metaiodobenzylguanidine single photon emission CT ma...

We report a three-phase bone scintigraphy for the diagnosis of a peripheral bone lesion caused by systemic sarcoidosis. A 32-year-old man with suspected osteomyelitis of the right forefinger underwent three-phase bone scintigraphy with Tc-99m hydroxymethylene diphosphonate (HMDP) and single-photon emission computed tomography/computed tomography (SPECT/CT). The lesion was rich in blood flow acc...

ing their permission to publish these cases. The histopathological examinations were performed at the National CJD Surveillance Unit by Dr James Ironside. Contributors: RdeS, JP, and DH raised the possibility of using single photon emission computed tomography as a diagnostic “pointer” in new variant Creutzfeldt-Jakob disease, and RdeS wrote the paper. AR, MT, and MZ discussed the core concept ...