Basophils are rare cells in the peripheral blood which have capability to infiltrate into skin. Invasion of basophils has been detected pruritic skin diseases, including atopic dermatitis, bullous pemphigoid, chronic spontaneous urticaria and contact dermatitis. In skin, important players inflammatory immune response, as they release Th2 cytokines, interleukin (IL)-4 IL-13, subsequently inducin...