The optic fissure is a transient gap in the developing vertebrate eye, which must be closed as development proceeds. A persisting optic fissure, coloboma, is a major cause for blindness in children. Although many genes have been linked to coloboma, the process of optic fissure fusion is still little appreciated, especially on a molecular level. We identified a coloboma in mice with a targeted i...

Introduction. The appearance of a coloboma of the iris must have been known long before Walther (15) introduced the term in 1821 since the condition is easiiy visible. The word coloboma is derived from the Greek and means the part which is taken away in mutilation or injury or the part that is lacking, that is, a defect. In coloboma iridis, therefore, a section of the iris is lacking, often bil...

For this literature review of pit and fissure sealant, 1,465 references were selected by a search for “sealants” on PubMed. References were limited to dental journals and papers in the English language. The search comprised papers from 1971 to October 2001. Additional papers of historical significance prior to 1971 were added from memory and from reference lists published in early papers. This ...

a r t i c l e i n f o a b s t r a c t Keywords: basaltic shield InSAR data sill radial dike circumferential fissure Galápagos Islands Space-geodetic measurements of surface deformation produced by the most recent eruptions at Fernandina – the most frequently erupting volcano in the Galápagos Archipelago – reveal that all have initiated with the intrusion of subhorizontal sills from a shallow ma...

OBJECTIVE To compare the symptomatic relief, healing and side-effects of topical diltiazem (DTZ) and glyceryl trinitrate in the treatment of chronic anal fissure. STUDY DESIGN Randomized controlled trial. PLACE AND DURATION OF STUDY The Surgical Outpatient Department of Civil Hospital, Karachi, from March 2006 to February 2007. METHODOLOGY Patients with chronic anal fissure were included ...

Introduction: Due to concerns about histological caries and recurrent caries after the use of sealants, adhesive systems containing fluoride and antibacterial agents have been proposed. The aim of this study was to evaluate the microleakage of sealants after the use of antibacterial chlorhexidine solution on etched enamel with and without the use of fifth- and sixth-generation adhesive systems....

The optic fissure is a transient gap in the developing optic cup of vertebrates. Persisting optic fissures, coloboma, are a frequent reason for blindness in children. Although many genes have been linked to coloboma, it has remained unclear how the two bi-layered epithelia comprising the optic fissure margins are fusing to form a continuous neuroretina and retinal pigmented epithelium (RPE) res...

PURPOSE To investigate whether the integrity (completeness) of pulmonary fissures affects pulmonary function in patients with chronic obstructive pulmonary disease (COPD). MATERIALS AND METHODS A dataset consisting of 573 CT exams acquired on different subjects was collected from a COPD study. According to the global initiative for chronic obstructive lung disease (GOLD) criteria, these subje...

RATIONALE Interlobar fissure integrity has previously correlated with responsiveness to endobronchial lung volume reduction therapy in patients with advanced emphysema. OBJECTIVE This report summarises the effect of interlobar fissure integrity on responses to treatment with a novel endoscopic tissue sealant (AeriSeal emphysematous lung sealant (ELS)) that collapses hyperinflated lung. METH...

Address for Correspondence: Dr. Y. Mamatha, Associate professor, Kodagu Institute of Medical Sciences, Madikeri, Karnataka State, India. E-Mail: [email protected] Background: The lungs are the essential organs of respiration. Fissures are an integral part of human lung. The fissures in lung enhance uniform expansion. These fissures may be complete, incomplete or absent. A detailed knowledge o...