BACKGROUND Atopic dermatitis (AD) is a public health problem, with an increasing prevalence worldwide. AD is a chronic inflammatory disease characterised by skin lesions and severe itching. Immunologically, AD has two forms, IgE-mediated and cell-mediated, but it may also be idiopathic. In the pathogenesis of AD, the gene mutations for filaggrin, a filament-aggregating protein present in the ep...

Eosinophilic esophagitis (EoE) is a chronic T helper 2-type inflammatory disorder. Concurrent allergic diseases have been observed in EoE cases at a high prevalence. The observation that EoE responds to dietary treatment suggests that EoE is an antigen-driven process. However, the pathogenesis by which allergens mediate the eosinophilic disease in the esophagus needs further clarification. In i...

The aim of this study was to present two cases of severe anaphylaxis during sentinel lymph node biopsy (SLNB). Case 1: A 64-year-old-woman had two months earlier been diagnosed with breast ductal invasive carcinoma by first local excision. She was taken for further surgery with SLNB. At induction she received midazolam, fentanyl, propofol, atracurium, cefazolin and paracetamol. She was given a ...

Background Wheat Dependent Exercise Induced Anaphylaxis (WDEIA) is a form of Food Dependent Exercise Induced Anaphylaxis. WDEIA occurs when there is an allergic reaction following the ingestion of wheat, coupled with exercise [1]. The suspected allergen that is responsible for WDEIA is omega5gliadin [2]. We report a series of adult clinical cases of WDEIA recorded between 2006-2009 at Health Sc...

Para-phenylenediamine (PPD) can induce immediate or - more often - delayed hypersensitivity. We report the case of 48-year old female admitted to the out-patient allergy clinic a day after her visit in a beauty parlour, where she had her eyelashes and eyebrows dyed with henna. Physical examination revealed prominent edema of the upper part of the face including forehead, cheeks and eyes causing...

BACKGROUND This study evaluated the diagnostic performance of the atopy patch test (APT) compared with skin prick testing (SPT) and in vitro IgE measurement in a large group of patients with atopic dermatitis (AD) with or without respiratory symptoms (RS). METHODS The study included 521 patients (292 males, 229 females; age, 0.5-18 years; median age, 6 years) with AD and RS with different cli...

Methods This study was a retrospective analysis of cases of patients referred to the Allergy Clinic of Rio de Janeiro General Policlinic with records of suggestive of AR to BL, in the period between February 2011 and July 2014. All the patients observed ENDA protocol: specific questionnaire of adverse drug reactions, IgE specific for penicillin G and V, amoxicillin and ampicillin, followed by s...

Allergy skin testing is considered a safe method for testing for IgE-mediated allergic responses although anaphylactic events can occur. Reported rates of anaphylaxis per patient are not consistent and range from 0.008 to 4%. The aim of this study was to determine the rate of epinephrine use associated with allergy skin-prick testing (SPT) and intradermal testing (IDT) in a suburban practice ov...

AIM To evaluate German cockroach (Blattella germanica) allergen levels in house dust and skin reactivity to German cockroach in adult atopic and non-atopic subjects in inland areas of Croatia. METHODS Blattella germanica group 2 (Bla g 2) allergen was measured using the enzyme-linked immunosorbent assay (ELISA) on test strips (Dustscreen(TM) test, Heska AG, Switzerland) in 94 house dust sampl...

Background Specific IgE to Ara h 2 as clinical predictor for peanut allergy in children has a diagnostic value comparable to a recently published prediction model containing gender, skin prick test (SPT), specific IgE (sIgE) to peanut extract and total IgE. The need for food challenges could be reduced by implicating both methods. In adults, the diagnostic value of peanut components has not bee...