Diabetic foot (DF) is one of the most severe complications diabetes that significantly reduces quality life and survival patients. Besides firmly established risk factors, novel data indicate alterations in lipid metabolism might also be implicated development progression DF. dyslipidemia characterized by atherogenic triad, consisting increased triglycerides (TG), decreased high-density lipopro...

The increase in cardiovascular morbidity and mortality associated to insulin resistance (IR) states (obesity, metabolic syndrome, type 2 diabetes) represents a major public health problem. In IR, dyslipidemia typically include hypertriglyceridemia, low high density lipoprotein cholesterol, increased small and dense low density lipoprotein particles, and post-prandial hyperlipidemia, which play ...

Metabolic syndrome is a clinical syndrome in which multiple risks are clustered in an individual and is a common basis of vascular disease in the industrial countries. Metabolic syndrome, dysmetabolic syndrome or insulinresistance syndrome (or syndrome X as it was initially designated), which is closely linked to insulin resistance, is a condition, which is recognized as raising the risk of car...

Eicosapentaenoic acid (EPA) is a triglyceride-lowering agent that reduces circulating levels of the apolipoprotein B (apoB)-containing lipoprotein particles small dense low-density lipoprotein (sdLDL), very-low-density lipoprotein (VLDL), and oxidized low-density lipoprotein (LDL). These benefits may result from the direct antioxidant effects of EPA. To investigate this potential mechanism, the...

A mathematical model describing the uptake of low density lipoprotein (LDL) and very low density lipoprotein (VLDL) particles by a single hepatocyte cell is formulated and solved. The model includes a description of the dynamic change in receptor density on the surface of the cell due to the binding and dissociation of the lipoprotein particles, the subsequent internalisation of bound particles...

Abstract Aim The aim of this study was to compare small dense low-density lipoprotein cholesterol (sd-LDL-c) and various lipid markers between patients exhibiting plaque rupture (PR) in the culprit lesions evaluated by optical coherence tomography (OCT) imaging those without PR ST-segment elevation myocardial infarction (STEMI) patients. Methods We studied consecutive 60 de novo with STEMI who ...