EM-Fold was used to build models for nine proteins in the maps of GroEL (7.7 Å resolution) and ribosome (6.4 Å resolution) in the ab initio modeling category of the 2010 cryo-electron microscopy modeling challenge. EM-Fold assembles predicted secondary structure elements (SSEs) into regions of the density map that were identified to correspond to either α-helices or β-strands. The assembly uses...

The purpose of this study was to explore how three different human resource variables affect employment growth of small-scale enterprises: Human capital of business owners, human capital of employees, and human resource development and utilization. The literature suggests different models how these human resource variables affect business outcomes. Longitudinal data from 119 German business own...

This paper aims to comprehend the intrinsic limitations of the market players in the financial system and how these create a situation of `missing middle` for small and medium industries (SME) financing in Bangladesh. A clear dualism prevails in the manufacturing industry of this country. While the SMEs maintains the biggest share in establishments and employment creation, large enterprises (LE...

innovation is the key to growth, without it, most organization would forever be stuck doing the same old things the same old way. new products, new services and new ways of doing business would never emerge. entrepreneurship activities brings about business innovation with resultant development in enterprises which also serves as a panacea to economic growth in developing countries. entrepreneu...

the corporate entrepreneurship (ce) of firms and enterprises is the subject of current research in the fields of management and business. however, analyses on this subject in agricultural firms are lacking. the purpose of this research was to study the relationships between corporate entrepreneurship and firm performance in agricultural small and medium-sized enterprises (asmes) in iran. specif...

The problem of comparison of structural similarity has been complex and computationally expensive. The first step to solve comparison of structural similarity in 3D structure databases is to develop fast methods for structural similarity. Therefore, we propose a new method of comparing structural similarity in protein structure databases by using topological patterns of proteins. In our approac...

With the ability to observe the activity from large numbers of neurons simultaneously using modern recording technologies, the chance to identify sub-networks involved in coordinated processing increases. Sequences of synchronous spike events (SSEs) constitute one type of such coordinated spiking that propagates activity in a temporally precise manner. The synfire chain was proposed as one pote...

[1] A large slow slip event (SSE) had been expected for the Guerrero gap for 2010. It was actually observed with an onset in July 2009. Comparison with the preceding large SSEs, which occurred in 2002 and 2006, highlights both persistent characteristics of the Guerrero SSEs (e.g. the localization of slip in the seismogenic part of the subduction interface), and also particularities of the 2009/...

BACKGROUND Real-world treatment patterns of bone metastatic castration-resistant prostate cancer (mCRPC) in Japan were examined, focusing on treatment patterns and resource use differences attributed to symptomatic skeletal events (SSEs). METHODS Urologists (N = 176) provided retrospective chart data for patients with mCRPC (N = 445) via online surveys. Descriptive analyses and chi-square tes...

UNLABELLED We introduce TOPS+ strings, a highly abstract string-based model of protein topology that permits efficient computation of structure comparison, and can optionally represent ligand information. In this model, we consider loops as secondary structure elements (SSEs) as well as helices and strands; in addition we represent ligands as first class objects. Interactions between SSEs and b...